about
Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular SystemLoss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues.Differential response of orthologous L,L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds.Solid-supported synthesis and biological evaluation of the lantibiotic peptide bis(desmethyl) lacticin 3147 A2.Synthetic Modification within the "RPRL" Region of Apelin Peptides: Impact on Cardiovascular Activity and Stability to Neprilysin and Plasma Degradation.The Metalloprotease Neprilysin Degrades and Inactivates Apelin Peptides.The Synthesis of Active and Stable Diaminopimelate Analogues of the Lantibiotic Peptide Lactocin SOrganohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics.Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom.Characterization and Biochemical Assays of Streptomyces Vanadium-Dependent Chloroperoxidases.Targeting the apelin pathway as a novel therapeutic approach for cardiovascular diseasesCorrection to Organohalogens Naturally Biosynthesized in Marine Environments and Produced As Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ DynamicsTotal Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural ProductsMacrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavageTotal Enzyme Syntheses of Napyradiomycins A1 and B1Nonlinear Biosynthetic Assembly of Alpiniamide by a Hybrid cis/trans-AT PKS-NRPSPlasma kallikrein cleaves and inactivates apelin-17: Palmitoyl- and PEG-extended apelin-17 analogs as metabolically stable blood pressure-lowering agentsSynthesis, bioactivity, and enzymatic modification of antibacterial thiotetromycin derivativesCariogenic Streptococcus mutans Produces Tetramic Acid Strain-Specific Antibiotics That Impair Commensal ColonizationBiosynthesis of l-4-Chlorokynurenine, an Antidepressant Prodrug and a Non-Proteinogenic Amino Acid Found in Lipopeptide AntibioticsScalable Biosynthesis of the Seaweed Neurochemical, Kainic AcidAlgal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into an N-prenyltransferaseComparative Genomics and Metabolomics in the Genus Nocardia
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description
investigador
@es
researcher
@en
name
Shaun M K McKinnie
@en
Shaun M K McKinnie
@nl
type
label
Shaun M K McKinnie
@en
Shaun M K McKinnie
@nl
prefLabel
Shaun M K McKinnie
@en
Shaun M K McKinnie
@nl
P31
P496
0000-0001-6776-6455