about
Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity.A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channelsSpecific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa.Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem.Cation currents in human airway epithelial cells induced by infection with influenza A virus.A Ba2+-resistant, acid-sensitive K+ conductance in Na+-absorbing H441 human airway epithelial cells.PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells.Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF.Complex CatSper-dependent and independent [Ca2+]i signalling in human spermatozoa induced by follicular fluid.Single-cell analysis of [Ca2+]i signalling in sub-fertile men: characteristics and relation to fertilization outcome.Differential phosphoinositide binding to components of the G protein-gated K+ channelHomozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacityNovel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function
P50
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Sean G Brown
@en
Sean G Brown
@nl
type
label
Sean G Brown
@en
Sean G Brown
@nl
prefLabel
Sean G Brown
@en
Sean G Brown
@nl
P31
P496
0000-0003-0767-0253