about
Tumor-Derived Cell Lines as Molecular Models of Cancer PharmacogenomicsCrowdsourcing biomedical research: leveraging communities as innovation enginesRhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer.Data pushing: a fly-centric guide to bioinformatics tools.Gene networks in Drosophila melanogaster: integrating experimental data to predict gene functionConcurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer.Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression."Reverse ecology" and the power of population genomicsCombined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy.Research resource: EPSLiM: ensemble predictor for short linear motifs in nuclear hormone receptors.DREAMTools: a Python package for scoring collaborative challenges.GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis.Troubleshooting microarray hybridizations.Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells.Differential splicing across immune system lineagesMultivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.A SPATIOTEMPORAL MODEL TO SIMULATE CHEMOTHERAPY REGIMENS FOR HETEROGENEOUS BLADDER CANCER METASTASES TO THE LUNG.Decade in review-bladder cancer: international progress: from cytology to genomics.Seeking the wisdom of crowds through challenge-based competitions in biomedical research.Community mining of open clinical trial data.Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.All Paths Lead to TRIM25.Systematic Review: Characteristics and Preclinical Uses of Bladder Cancer Cell Lines.Simulating heterogeneous populations using Boolean models.GSEA-InContext: identifying novel and common patterns in expression experiments.A Whole-genome CRISPR Screen Identifies a Role of MSH2 in Cisplatin-mediated Cell Death in Muscle-invasive Bladder CancerTargeting DDR2 enhances tumor response to anti-PD-1 immunotherapyEya3 promotes breast tumor-associated immune suppression via threonine phosphatase-mediated PD-L1 upregulationNext-Generation Machine Learning for Biological NetworksTrisomy 21 activates the kynurenine pathway via increased dosage of interferon receptorsSIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell ProgramA Gene Expression Signature Predicts Bladder Cancer Cell Line Sensitivity to EGFR InhibitionMetastatic cells are preferentially vulnerable to lysosomal inhibitionA DREAM Challenge to Build Prediction Models for Short-Term Discontinuation of Docetaxel in Metastatic Castration-Resistant Prostate CancerMesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple CancersLoss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous RecombinationMonocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid LeukemiaA SIX1/EYA2 small molecule inhibitor disrupts EMT and metastasis
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
James Costello
@en
James Costello
@nl
type
label
James Costello
@en
James Costello
@nl
prefLabel
James Costello
@en
James Costello
@nl
P31
P496
0000-0003-3158-9682