about
Investigation of a MMP-2 activity-dependent anchoring probe for nuclear imaging of cancerNECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells.Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.A membrane protease regulates energy production in macrophages by activating hypoxia-inducible factor-1 via a non-proteolytic mechanismTargeting the Warburg effect that arises in tumor cells expressing membrane type-1 matrix metalloproteinaseThe ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux.Mint3 potentiates TLR3/4- and RIG-I-induced IFN-β expression and antiviral immune responses.Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virusIdentification and characterization of Lutheran blood group glycoprotein as a new substrate of membrane-type 1 matrix metalloproteinase 1 (MT1-MMP): a systemic whole cell analysis of MT1-MMP-associating proteins in A431 cells.Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP.Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock.Mint3 in bone marrow-derived cells promotes lung metastasis in breast cancer model mice.Integrated functions of membrane-type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase.MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells.ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.ZF21 protein regulates cell adhesion and motility.Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth.Deficiency of a membrane skeletal protein, 4.1G, results in myelin abnormalities in the peripheral nervous system.Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment.The membrane palmitoylated protein, MPP6, is involved in myelin formation in the mouse peripheral nervous systemElectron microscopic observation of photoreceptor cells in directly inserted anesthetized Drosophila into a high-pressure freezing unitScaffold protein Lin7 family in membrane skeletal protein complex in mouse seminiferous tubules
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Q28540644-93313DA3-29EB-4F39-A47C-444EB24266F3Q33292144-3E601332-C7F6-464B-BF92-54EB2BCB9027Q33782573-D003388A-630B-4FC5-A4E3-FB519518A12EQ34144698-3053CEF0-240D-4201-B671-2E881EF88E5BQ34800574-F42E6A4E-86E3-48AE-95FF-B86C132C967CQ37125226-06B54694-BBC1-4AD0-8077-F4AF7FFF4774Q37369228-7B86A5B7-E742-4C69-AE28-DC2F16819D2AQ37435310-966E8D05-7C07-4AFB-82AF-A30EBDF5CDC6Q37448014-A4E91310-5790-4E0D-AE21-FCE2085D9BDDQ37546037-830E7BB4-B4D4-4CC4-8D21-FCF01F3D1D76Q38420209-C5A26978-9B3B-4B2F-81AA-D7F23B90B26EQ38699620-874636BD-FB6D-4AFE-A412-A70156D7EA39Q39165910-D38450C0-372E-4D82-87A7-7BB650E2AC60Q39356616-D6D9B2F2-236F-4DE1-B737-7C13FAFC9D2BQ39648566-4A1041C5-7D9E-456F-B00F-7EB43841BCF2Q39707936-50B6FC95-2846-4717-80DA-6C8164D536F4Q40136524-214C6E7E-CAF2-40C3-96D0-60A1FC67331AQ40201346-CAF1A044-6A6F-4D16-9F02-912D79102DF2Q48014150-2EEF413C-972F-4FA4-9263-0B25519027D1Q52655046-354A5055-2564-45E6-ACB5-C881F4184E6BQ57791605-3268CDCF-5154-4950-A1CC-FF4646136942Q90734253-31EE53FB-FEA9-486A-B199-EB72B8835945Q92607324-2CF041A8-C22F-42FA-8960-2F588073ECF1
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Takeharu Sakamoto
@en
Takeharu Sakamoto
@nl
type
label
Takeharu Sakamoto
@en
Takeharu Sakamoto
@nl
prefLabel
Takeharu Sakamoto
@en
Takeharu Sakamoto
@nl
P31
P496
0000-0002-1225-1902