about
Antischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoniHeme as trigger and target for trioxane-containing antimalarial drugs.Schistosomiasis chemotherapy.The Necessity of Having a Tetradentate Ligand to Extract Copper(II) Ions from Amyloids.The antimalarial trioxaquine DU1301 alkylates heme in malaria-infected mice.Correlation between Plasmodium yoelii nigeriensis susceptibility to artemisinin and alkylation of heme by the drug.Transfer of Copper from an Amyloid to a Natural Copper-Carrier Peptide with a Specific Mediating Ligand.Regulation of copper and iron homeostasis by metal chelators: a possible chemotherapy for Alzheimer's disease.Trioxaferroquines as new hybrid antimalarial drugs.In vitro activities of trioxaquines against Schistosoma mansoni.Alkylating ability of artemisinin after Cu(I)-induced activation.Endoperoxide-based compounds: cross-resistance with artemisinins and selection of a Plasmodium falciparum lineage with a K13 non-synonymous polymorphism.Characterization of new specific copper chelators as potential drugs for the treatment of Alzheimer's disease.Preparation of new tetradentate copper chelators as potential anti-Alzheimer agents.N4-Tetradentate chelators efficiently regulate copper homeostasis and prevent ROS production induced by copper-amyloid-β1-16, even in the presence of an excess of zinc.Peroxide bond strength of antimalarial drugs containing an endoperoxide cycle. Relation with biological activity.Involvement of Pazopanib and Sunitinib Aldehyde Reactive Metabolites in Toxicity and Drug-Drug Interactions in Vitro and in Patient SamplesMetalloporphyrin-Catalyzed Oxidation of Sunitinib and Pazopanib, Two Anticancer Tyrosine Kinase Inhibitors: Evidence for New Potentially Toxic MetabolitesMagnetite Fe3 O4 Has no Intrinsic Peroxidase Activity, and Is Probably not Involved in Alzheimer's Oxidative StressMetal Ions in Alzheimer's Disease: A Key Role or Not?Small Molecules: The Past or the Future in Drug Innovation?
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Anne Robert
@en
Anne Robert
@nl
type
label
Anne Robert
@en
Anne Robert
@nl
prefLabel
Anne Robert
@en
Anne Robert
@nl
P31
P496
0000-0002-9092-6776