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Animal Models of Bone Loss in Inflammatory Arthritis: from Cytokines in the Bench to Novel Treatments for Bone Loss in the Bedside-a Comprehensive ReviewTargeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosisPALS1 is essential for retinal pigment epithelium structure and neural retina stratification.Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced ArthritisThe CRB1 and adherens junction complex proteins in retinal development and maintenance.5Alpha-dihydrotestosterone up-regulates transthyretin levels in mice and rat choroid plexus via an androgen receptor independent pathway.Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.17beta-estradiol induces transthyretin expression in murine choroid plexus via an oestrogen receptor dependent pathway.AAV Gene Augmentation Therapy for CRB1-Associated Retinitis Pigmentosa.Transthyretin is up-regulated by sex hormones in mice liver.Experimental Arthritis Mouse Models Driven by Adaptive and/or Innate Inflammation.Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and functionCrumbs2 mediates ventricular layer remodelling to form the spinal cord central canalCD4+ CCR6+ T cells, but not γδ T cells, are important for the IL-23R-dependent progression of antigen-induced inflammatory arthritis in miceMicroglial Cell Dysfunction in CRB1-Associated RetinopathiesCRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast SensitivityMicroglia Contribution to the Regulation of the Retinal and Choroidal Vasculature in Age-Related Macular Degeneration
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investigador
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researcher
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wetenschapper
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C H Alves
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C H Alves
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C H Alves
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C H Alves
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C H Alves
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C H Alves
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0000-0001-9776-5701