about
Bax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranesThe rheostat in the membrane: BCL-2 family proteins and apoptosisVisual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes.Caspase-independent mitochondrial cell death results from loss of respiration, not cytotoxic protein release.Bioenergetics and cell death.Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death.Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency.Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilizationPhenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1
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Q28483986-D077122B-1EDC-4503-A149-388091FC8A8FQ34038716-FA46A7D0-7C23-4847-9F94-AF7FCBEF6E47Q34960771-2381FF95-22AE-4E36-814A-6013A80D0AC2Q37448270-CBDB3DE5-0CE7-4C7A-8085-CD828AC3AA41Q37774677-B290F969-2AEA-4D12-946B-F503F1FDEB2FQ41855874-21CC0728-25BB-4582-B030-04FA74749056Q42381310-F6172182-ADF5-41CD-A973-49EB55260082Q43099640-3A67B4D1-7F5B-4D49-A552-FC543F7A40CCQ92412015-EA9C7F5D-0B19-4D68-935A-6A4AC9FC1F64Q92632027-44D87813-CAF2-48FB-8B34-16E086B1FEBD
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Donald D Newmeyer
@en
Donald D Newmeyer
@nl
type
label
Donald D Newmeyer
@en
Donald D Newmeyer
@nl
prefLabel
Donald D Newmeyer
@en
Donald D Newmeyer
@nl
P31
P496
0000-0003-1736-2780