about
Guidelines for the use and interpretation of assays for monitoring autophagyThe Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation.Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation.Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation.Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitorsDesign, synthesis and biological evaluation of arylcinnamide hybrid derivatives as novel anticancer agentsSynthesis and in vitro evaluation of 3h-pyrrolo[3,2-f]-quinolin-9-one derivatives that show potent and selective anti-leukemic activityNovel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluationSynthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents.Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analoguesDesign, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-ImidazoleDifferentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives.Recent advances in vascular disrupting agents in cancer therapy.Vascular disrupting activity of combretastatin analogues.The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastomaA novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents.Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/β-catenin signaling.New more polar symmetrical bipyridinic compounds: new strategy for the inhibition of choline kinase α1.Natural daucane sesquiterpenes with antiproliferative and proapoptotic activity against human tumor cells.The phototoxicity of fluvastatin, an HMG-CoA reductase inhibitor, is mediated by the formation of a benzocarbazole-like photoproduct.Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and NoxaZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.Synthesis and fluorosolvatochromism of 3-arylnaphtho[1,2-b]quinolizinium derivatives.Targeting tubulin polymerization by novel 7-aryl-pyrroloquinolinones: Synthesis, biological activity and SARs.Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents.Kinome expression profiling of human neuroblastoma tumors identifies potential drug targets for ultra high-risk patients.Control of the DNA-Binding and Antiproliferative Properties of Hydroxybenzo[b]quinolizinium Derivatives with pH and Light.Ribociclib, A Cdk4/Cdk6 Kinase Inhibitor, Enhances Glucocorticoid Sensitivity In B-Acute Lymphoblastic Leukemia (B-All).TP-0903 inhibits neuroblastoma cell growth and enhances the sensitivity to conventional chemotherapy.NPM-ALK expression levels identify two distinct subtypes of paediatric anaplastic large cell lymphoma.Improvement and extension of anti-EGFR targeting in breast cancer therapy by integration with the Avidin-Nucleic-Acid-Nano-AssembliesBMP9 counteracts the tumorigenic and pro-angiogenic potential of glioblastomaPhytosterol and γ-Oryzanol Conjugates: Synthesis and Evaluation of their Antioxidant, Antiproliferative, and Anticholesterol ActivitiesCholine Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast CancerEB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells
P50
Q21996341-21AFEDD0-A2A2-4C8D-84CA-D7676A0975B1Q27341833-CF8B0EE5-1DAD-485C-8ECE-A7D16E52A05FQ33560133-F4A29469-84C8-4E71-A4FB-316314BECB5CQ33830002-A7A5BA6B-DE7B-4C4B-8250-4673ED74B1D3Q33844410-D0B8B550-E4AC-4010-B818-2831D1AE09E3Q33880696-37F352D4-28F5-4BC4-9E25-E3FC2F24396FQ33889395-0E45FEB1-0725-408C-9624-CB2CEA2BF0F5Q34066044-E81BD798-A2F8-4AAE-ABC2-F04F76C9650EQ34083310-C7E2C2C8-9BE0-4A8A-B0A7-473D5B407693Q34783706-01337E5B-1164-4A20-BF75-878E2A35A540Q35532093-32F72B58-45AC-41E9-87A1-0266360880E8Q36079759-D407ED24-2642-4268-A5BB-8DC7AEAE96C6Q36185346-5B3214A9-710A-4CA3-A8D2-B647FBEB3D1EQ36389900-B0930DCB-77DA-4A2B-A3E2-E7E4D492B4A7Q36748138-A0617E25-C200-4377-B29F-FB20FA779F41Q36928505-19636ED6-49C3-4A84-B35B-E805F34FC2FFQ37590391-F34695A7-D073-459E-8658-2E22FA637F10Q38264533-4E2ABF87-5D95-4F4B-AA57-0901DA80ACE8Q38767839-0F5EF9ED-1451-4A53-8BAD-6F2EABB67F5FQ38834089-B39754E7-43B0-4695-9BC0-9F11FB5436F9Q38979471-1A20FEB6-6BE5-48E4-B342-843529511988Q38982593-5A630103-1BC1-4D5D-8EBA-8D6EAE61ACECQ39017908-0B6D866F-099F-4930-A104-F64CBBF4E5AAQ39480758-6D7A054D-604E-4CE5-8A73-B7BA2A8247D2Q39674324-F561C722-21E6-45F4-B005-52353117E2D3Q41808352-7E7D152C-C170-4EF1-9353-DE44EA1DAC26Q42265722-2A5A5FA8-8C6B-43F9-80C0-FE2F5559ECCDQ42576050-BD6248F8-6C4F-42E9-8C2F-76451AEA7B2AQ46249448-D199B079-D091-4D7F-BB12-B8979ADBA537Q46381337-844E7188-62CF-4395-A0D3-5A3D906FC4DDQ47715440-E815578F-AB85-466E-9673-1433014911ADQ48290499-21E09707-E22E-42B4-BA6B-AB99B993D410Q48510554-F947F070-58E1-4BB5-A444-B733C5CF981EQ49866304-64657482-FD2E-4CFE-B17C-FBB940CDFF45Q51367632-047B6635-FC20-4F8F-A878-170DC25EF5F9Q57030083-898B73E1-002C-4442-8C9B-C8C54021764EQ57177045-A1D08FD0-FE09-4129-BCBD-6C7B43E3BC2FQ58545811-8AC2F138-7F61-4E18-A38F-6C834687165EQ58579238-BF7498AE-CD72-462A-B1D0-2440286084A4Q61543574-DC766BB6-B5FA-4BDD-9A0E-B474B1E3F2E5
P50
description
investigador
@es
researcher
@en
name
Giampietro Viola
@en
type
label
Giampietro Viola
@en
prefLabel
Giampietro Viola
@en
P31
P496
0000-0001-9329-165X