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Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cellsThe relationship of JAK2(V617F) and acquired UPD at chromosome 9p in polycythemia vera.β-Thalassemia due to intronic LINE-1 insertion in the β-globin gene (HBB): molecular mechanisms underlying reduced transcript levels of the β-globin(L1) alleleRUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling.Novel homozygous VHL mutation in exon 2 is associated with congenital polycythemia but not with cancer.Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer.HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy.Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera.The homozygous VHL(D126N) missense mutation is associated with dramatically elevated erythropoietin levels, consequent polycythemia, and early onset severe pulmonary hypertension.Co-occurring V617F and R1063H mutations increase JAK2 signaling and neutrophilia in MPN patientsWnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer CellsIron chelation and 2-oxoglutarate-dependent dioxygenase inhibition suppress mantle cell lymphoma's cyclin D1Experimental Modeling of Myeloproliferative NeoplasmsAddiction to DUSP1 protects JAK2V617F-driven polycythemia vera progenitors against inflammatory stress and DNA damage, allowing chronic proliferation
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Lucie Lanikova
@en
Lucie Lanikova
@nl
type
label
Lucie Lanikova
@en
Lucie Lanikova
@nl
prefLabel
Lucie Lanikova
@en
Lucie Lanikova
@nl
P108
P31
P496
0000-0002-2845-8692