about
Prion shedding from olfactory neurons into nasal secretionsStructure of the Flexible Amino-Terminal Domain of Prion Protein Bound to a Sulfated GlycanAnchorless prion protein results in infectious amyloid disease without clinical scrapiePrion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuICAnti-prion activity of a panel of aromatic chemical compounds: in vitro and in silico approachesParallel in-register intermolecular β-sheet architectures for prion-seeded prion protein (PrP) amyloids.Charge neutralization of the central lysine cluster in prion protein (PrP) promotes PrP(Sc)-like folding of recombinant PrP amyloids.Prion Protein Prolines 102 and 105 and the Surrounding Lysine Cluster Impede Amyloid Formation.Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions.Subclinical scrapie infection in a resistant species: persistence, replication, and adaptation of infectivity during four passages.Advanced tests for early and accurate diagnosis of Creutzfeldt-Jakob disease.New inhibitors of scrapie-associated prion protein formation in a library of 2000 drugs and natural products.Structural properties of prion protein protofibrils and fibrils: an experimental assessment of atomic models.Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion StrainsEnhanced neuroinvasion by smaller, soluble prions.Heparin binding confers prion stability and impairs its aggregation.Designed Trpzip-3 β-Hairpin Inhibits Amyloid Formation in Two Different Amyloid SystemsRapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassaysMammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactorsDesigned α-sheet peptides inhibit amyloid formation by targeting toxic oligomers.Biomedicine. A view from the top--prion diseases from 10,000 feet.A test for Creutzfeldt-Jakob disease using nasal brushings.Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting diseaseMefloquine, an antimalaria drug with antiprion activity in vitro, lacks activity in vivoA porphyrin increases survival time of mice after intracerebral prion infectionMouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res.Potent antiscrapie activities of degenerate phosphorothioate oligonucleotides.Age-related differences in neuroinflammatory responses associated with a distinct profile of regulatory markers on neonatal microglia.The most infectious prion protein particles.Inhibition of protease-resistant prion protein accumulation in vitro by curcuminRapid antemortem detection of CWD prions in deer saliva.Is PrP the road to ruin?Effect of glycans and the glycophosphatidylinositol anchor on strain dependent conformations of scrapie prion protein: improved purifications and infrared spectra.Prion disease blood test using immunoprecipitation and improved quaking-induced conversionPrion strain-dependent differences in conversion of mutant prion proteins in cell culture.Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid.Enhanced antiscrapie effect using combination drug treatmentPrion proteins meet protein quality control.Detection and discrimination of classical and atypical L-type bovine spongiform encephalopathy by real-time quaking-induced conversionPrion protein conversions: insight into mechanisms, TSE transmission barriers and strains.
P50
Q27315129-CC6D2984-B0E0-48AB-94F0-532750354B37Q27658157-6A5C8612-14FD-4689-A575-03B4BB29ABE7Q28254406-6C736963-104A-49DD-9845-333975AD5966Q28484853-A1AEBBB1-2936-4413-B58A-5EBCFD694A54Q28538336-320BC548-7053-4B9A-B13A-75C1326FB8D4Q30364768-6576D98C-4449-4548-8B9A-93F3DD3F9000Q30368863-ED18285D-B2BE-4A99-B145-603F36C83C77Q30376712-048D3BBB-5E6B-4928-AF04-2FC7904AA150Q30492360-9DA3F336-4331-4CF4-B284-E9E952376577Q30746165-2BEC6D97-D16A-4A07-A008-6C2737C59CF3Q31095751-EFC7D0E0-1A42-4949-9FBB-0692BA722D04Q31156724-200D8E57-11F8-4AE9-8E6A-1149E4ECB303Q33343542-27E1698F-FBD9-411E-9ADE-83A27FE56B18Q33457447-B463E27A-E7E9-43EF-B91D-43EDFB11E16EQ33588967-AFAEFE0C-BBF9-4B12-BC6D-2FDCF8CDC778Q33613234-95372D92-F1E9-4C47-A7A2-A186AFAAD9F2Q33635955-2A4A9A63-925B-41F9-B547-3C9758CDF327Q33769767-72DC834E-9279-4CC2-839A-AE877D723CEEQ33824971-92505575-1476-451D-BE29-4A9981C6F1A9Q33878699-7FC08409-0E04-405E-984F-C57C42A576E0Q34195825-D142D9E1-3630-4865-A093-BE393015DD04Q34293962-60D93B7A-A8FA-4154-8C15-41C9397C483BQ34301796-1E190E59-C04D-4950-8192-D559190FE8B3Q34301832-C1924882-5E23-49C4-8F06-3F9C9180030DQ34352240-072E60C4-999F-4D07-87CB-DF7D5E8AB65BQ34434726-3DC62A1F-1249-4C05-9AF9-3B149088B021Q34509751-9094864E-1182-482D-AC59-3F83232238C9Q34523373-5EB06CFE-5214-4D2A-BEC7-7D589090F494Q34805737-C48BDCA9-99DC-4866-9E35-B36FA2C7CFF6Q34976098-ED31D677-46C1-46E7-BF5E-1B9C86C3FFE2Q34989982-63F8A473-5E32-4CE5-8C51-B3503FC1B160Q34994003-D09E7D17-B198-4D4B-951A-42B333740CD9Q35004394-C7D9E5D3-9B8C-4F20-AAF9-B7E2A208076EQ35006294-D8192A08-9F2F-4466-9465-D69851280B14Q35023923-597A43BD-823F-42D2-AAA2-CF25F76EEA20Q35038237-3BA214EC-538A-4CC2-8397-14B5F41E556FQ35091582-91466FC2-61A9-4511-A855-2F7DD58AB3CDQ35167510-365903A3-BA84-43A9-8231-C3319713B671Q35193339-94A0168C-C653-46F0-8705-4E0C3AEFC2DDQ35548986-DEE0A5AA-DC5D-43EF-94F3-6678622A44B3
P50
name
Byron Caughey
@en
type
label
Byron Caughey
@en
prefLabel
Byron Caughey
@en