about
Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligaseMitochondrial trafficking in neurons and the role of the Miro family of GTPase proteins.Miro sculpts mitochondrial dynamics in neuronal health and disease.Ubiquitination at the mitochondria in neuronal health and disease.DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites.Miro proteins coordinate microtubule- and actin-dependent mitochondrial transport and distribution.Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.TDP-43 mutations increase HNRNP A1-7B through gain of splicing functionC9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1ACytoplasmic functions of TDP-43 and FUS and their role in ALSPeroxisomal fission is modulated by the mitochondrial Rho-GTPases, Miro1 and Miro2
P50
Q33652051-FFB3BA05-E4BC-492A-8320-5BFBADB6B095Q38164382-DA82F83E-5248-42A5-ACD2-0076CB4EBE20Q38680421-A452A1B9-E7A0-498D-839A-4A790393FEC3Q39437191-45D6E957-0D45-4682-933C-F760AB967D6AQ43100153-513766FA-FFA6-4538-8D28-1D8334F8481DQ47223177-528FEE0B-6B8D-40A6-973F-BE14EA61CBEFQ54989348-8A1F605D-5C83-47FD-A042-66DC049A5E3AQ58553474-38A34AA7-B9D4-487E-B9EE-75D032309558Q63859498-82E9FC9E-DAB0-4AEC-AF4B-D88E5747B9D3Q92317222-73260DBC-7D00-4285-94BD-10A0ABA86942Q92369041-95531335-3609-4AC3-8DEB-5F6CCD5BFCD2
P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Nicol Birsa
@en
Nicol Birsa
@nl
type
label
Nicol Birsa
@en
Nicol Birsa
@nl
prefLabel
Nicol Birsa
@en
Nicol Birsa
@nl
P31
P496
0000-0002-8271-540X