about
Selenophene and thiophene-core estrogen receptor ligands that inhibit motility and development of parasitic stages of Haemonchus contortus.Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparumChemistry: Chemical con artists foil drug discovery.The promise and peril of chemical probes.Hypotensive effects of ghrelin receptor agonists mediated through a novel receptor.Histone acetyltransferase inhibitors: where art thou?Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides.Screening-based translation of public research encounters painful problems.Defining the mechanisms by which the reactive oxygen species by-product, 4-hydroxynonenal, affects human sperm cell function.GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity.Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors.Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017-Utility and Limitations.Correspondence: Reply to 'Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury'.Reviewing hit discovery literature for difficult targets: glutathione transferase omega-1 as an example.Optimization of Novel 1-Methyl-1H-Pyrazole-5-carboxamides Leads to High Potency Larval Development Inhibitors of the Barber's Pole WormNovel 1-Methyl-1 H-pyrazole-5-carboxamide Derivatives with Potent Anthelmintic ActivityStructure-Activity Relationship Studies of Tolfenpyrad Reveal Subnanomolar Inhibitors of Haemonchus contortus DevelopmentAction plan for hit identification (APHID): KAT6A as a case studyDevelopment of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 InhibitorsDiscovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents3,3'-Disubstituted 5,5'-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial ActivitySubstituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor AgonistsDiscovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A
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P50
description
researcher
@en
name
Jonathan B Baell
@en
type
label
Jonathan B Baell
@en
prefLabel
Jonathan B Baell
@en
P31
P496
0000-0003-2114-8242