about
Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4.Statistical models suggest presence of two distinct subpopulations of miniature EPSCs in fast-spiking interneurons of rat prefrontal cortex.Non-classical mechanism of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor channel block by fluoxetine.The Effect of Hydrophobic Monoamines on Acid-Sensing Ion Channels ASIC1B.Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels.Potentiation and Block of ASIC1a by Memantine.Complex action of tyramine, tryptamine and histamine on native and recombinant ASICs.Histamine selectively potentiates acid-sensing ion channel 1a.Predicting Structural Details of the Sodium Channel Pore Basing on Animal Toxin StudiesHydrophobic Amines and Their Guanidine Analogues Modulate Activation and Desensitization of ASIC3Ligands of Acid-Sensing Ion Channel 1a: Mechanisms of Action and Binding SitesLidocaine and carbamazepine inhibit while phenytoin and lamotrigine paradoxically enhance the insect neuromuscular transmissionIntersegment contacts determine geometry of the open and closed states in P-loop channelsExtremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIAModulation of Proton-Gated Channels by Antidepressants
P50
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P50
description
researcher (ORCID 0000-0001-8523-4305)
@en
wetenschapper
@nl
name
Denis B Tikhonov
@en
Denis B Tikhonov
@nl
type
label
Denis B Tikhonov
@en
Denis B Tikhonov
@nl
prefLabel
Denis B Tikhonov
@en
Denis B Tikhonov
@nl
P31
P496
0000-0001-8523-4305