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Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intakeEvidence that intermittent, excessive sugar intake causes endogenous opioid dependenceGlutamatergic input to the lateral hypothalamus stimulates ethanol intake: role of orexin and melanin-concentrating hormoneOpioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens.A high-fat meal, or intraperitoneal administration of a fat emulsion, increases extracellular dopamine in the nucleus accumbens.Pharmacological interventions for binge eating: lessons from animal models, current treatments, and future directions.Reduced accumbens dopamine in Sprague-Dawley rats prone to overeating a fat-rich diet.High-fructose corn syrup causes characteristics of obesity in rats: increased body weight, body fat and triglyceride levels.Differential role of D1 and D2 receptors in the perifornical lateral hypothalamus in controlling ethanol drinking and food intake: possible interaction with local orexin neurons.Hypothalamic peptides controlling alcohol intake: differential effects on microstructure of drinking boutsFluoxetine alleviates behavioral depression while decreasing acetylcholine release in the nucleus accumbens shell.A high-fat diet prevents and reverses the development of activity-based anorexia in ratsNatural addiction: a behavioral and circuit model based on sugar addiction in rats.Baclofen suppresses binge eating of pure fat but not a sugar-rich or sweet-fat diet.Rats that binge eat fat-rich food do not show somatic signs or anxiety associated with opiate-like withdrawal: implications for nutrient-specific food addiction behaviors.Effects of perinatal exposure to palatable diets on body weight and sensitivity to drugs of abuse in rats.Opioids in the perifornical lateral hypothalamus suppress ethanol drinking.Accumbens dopamine-acetylcholine balance in approach and avoidance.Sugar and fat bingeing have notable differences in addictive-like behaviorOverlaps in the nosology of substance abuse and overeating: the translational implications of "food addiction".Activity-based anorexia is associated with reduced hippocampal cell proliferation in adolescent female rats.Positive relationship between dietary fat, ethanol intake, triglycerides, and hypothalamic peptides: counteraction by lipid-lowering drugsOpioids in the hypothalamic paraventricular nucleus stimulate ethanol intake.Sugar bingeing in rats.Opioids in the nucleus accumbens stimulate ethanol intake.After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalance.Inhibition of cocaine self-administration by fluoxetine or D-fenfluramine combined with phentermine.Amphetamine-sensitized rats show sugar-induced hyperactivity (cross-sensitization) and sugar hyperphagia.Cholecystokinin combined with serotonin in the hypothalamus limits accumbens dopamine release while increasing acetylcholine: a possible satiation mechanism.Effect of ethanol on hypothalamic opioid peptides, enkephalin, and dynorphin: relationship with circulating triglycerides.Elevated D3 dopamine receptor mRNA in dopaminergic and dopaminoceptive regions of the rat brain in response to morphine.Extracellular glutamate increases in the lateral hypothalamus during meal initiation, and GABA peaks during satiation: microdialysis measurements every 30 s.GS 455534 selectively suppresses binge eating of palatable food and attenuates dopamine release in the accumbens of sugar-bingeing rats.Ethanol intake increases galanin mRNA in the hypothalamus and withdrawal decreases it.Overlapping peptide control of alcohol self-administration and feeding.Opiate-like effects of sugar on gene expression in reward areas of the rat brain.Ethanol intake is increased by injection of galanin in the paraventricular nucleus and reduced by a galanin antagonist.Galanin microinjection in the third ventricle increases voluntary ethanol intake.Acetylcholine in the accumbens is decreased by diazepam and increased by benzodiazepine withdrawal: a possible mechanism for dependency.Bingeing, self-restriction, and increased body weight in rats with limited access to a sweet-fat diet.
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P50
name
Bartley G Hoebel
@en
Bartley G Hoebel
@nl
type
label
Bartley G Hoebel
@en
Bartley G Hoebel
@nl
prefLabel
Bartley G Hoebel
@en
Bartley G Hoebel
@nl