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Q28214436-1C9146B5-2126-4525-B4DD-81D8AC60283D
Q28214436-1C9146B5-2126-4525-B4DD-81D8AC60283D
BestRank
Statement
http://www.wikidata.org/entity/statement/Q28214436-1C9146B5-2126-4525-B4DD-81D8AC60283D
Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators
P2860
Q28214436-1C9146B5-2126-4525-B4DD-81D8AC60283D
BestRank
Statement
http://www.wikidata.org/entity/statement/Q28214436-1C9146B5-2126-4525-B4DD-81D8AC60283D
rank
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wasDerivedFrom
18145d7cf0209949ca2caddc66b905466e212f96
P2860
Different positioning of the ligand-binding domain helix 12 and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonists.