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Q33419789-4CB42BCE-A082-493A-8589-7573D18355B2
Q33419789-4CB42BCE-A082-493A-8589-7573D18355B2
BestRank
Statement
http://www.wikidata.org/entity/statement/Q33419789-4CB42BCE-A082-493A-8589-7573D18355B2
MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies.
P2860
Q33419789-4CB42BCE-A082-493A-8589-7573D18355B2
BestRank
Statement
http://www.wikidata.org/entity/statement/Q33419789-4CB42BCE-A082-493A-8589-7573D18355B2
rank
NormalRank
type
BestRank
Statement
wasDerivedFrom
16c0f40766e582a6474aa8d1fb4b88ef7ab75f6b
P2860
GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death.