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Q34318485-F58A3E0C-8FBD-4630-8F6D-466589C6CC3E
Q34318485-F58A3E0C-8FBD-4630-8F6D-466589C6CC3E
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34318485-F58A3E0C-8FBD-4630-8F6D-466589C6CC3E
The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.
P2860
Q34318485-F58A3E0C-8FBD-4630-8F6D-466589C6CC3E
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34318485-F58A3E0C-8FBD-4630-8F6D-466589C6CC3E
rank
NormalRank
type
BestRank
Statement
wasDerivedFrom
0c21d9c24c45c976f5ef3356117ea77fd220394c
P2860
The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.