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Q34748891-7FD17D71-1DDD-4035-85B9-CD9258F8567E
Q34748891-7FD17D71-1DDD-4035-85B9-CD9258F8567E
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34748891-7FD17D71-1DDD-4035-85B9-CD9258F8567E
Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis.
P2860
Q34748891-7FD17D71-1DDD-4035-85B9-CD9258F8567E
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34748891-7FD17D71-1DDD-4035-85B9-CD9258F8567E
rank
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type
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Statement
wasDerivedFrom
469ee22592bb877a47254fb50eeaf2175bef8981
P2860
Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops.