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Q34992813-8DDB9362-2C0E-4CF8-BD08-99E2FFE25399
Q34992813-8DDB9362-2C0E-4CF8-BD08-99E2FFE25399
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http://www.wikidata.org/entity/statement/Q34992813-8DDB9362-2C0E-4CF8-BD08-99E2FFE25399
DFG-out mode of inhibition by an irreversible type-1 inhibitor capable of overcoming gate-keeper mutations in FGF receptors.
P2860
Q34992813-8DDB9362-2C0E-4CF8-BD08-99E2FFE25399
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34992813-8DDB9362-2C0E-4CF8-BD08-99E2FFE25399
rank
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type
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Statement
wasDerivedFrom
9f53f10be2836987d54328b71bef27f0076f95bd
P2860
Structural Characterization of Proline-rich Tyrosine Kinase 2 (PYK2) Reveals a Unique (DFG-out) Conformation and Enables Inhibitor Design