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Q35023693-ABEFBD5C-69E9-4240-9287-D2E8BB8C512B
Q35023693-ABEFBD5C-69E9-4240-9287-D2E8BB8C512B
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Statement
http://www.wikidata.org/entity/statement/Q35023693-ABEFBD5C-69E9-4240-9287-D2E8BB8C512B
Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs survival of mice with experimental brain tumors.
P2860
Q35023693-ABEFBD5C-69E9-4240-9287-D2E8BB8C512B
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35023693-ABEFBD5C-69E9-4240-9287-D2E8BB8C512B
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wasDerivedFrom
adae634e8a02eb6520a64098756a9255d3615287
P2860
The second-site mutation in the herpes simplex virus recombinants lacking the gamma134.5 genes precludes shutoff of protein synthesis by blocking the phosphorylation of eIF-2alpha