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1
Q35096900-C42AC2A8-2198-4721-95F4-5376F16D166E
Q35096900-C42AC2A8-2198-4721-95F4-5376F16D166E
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35096900-C42AC2A8-2198-4721-95F4-5376F16D166E
Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia
P2860
Q35096900-C42AC2A8-2198-4721-95F4-5376F16D166E
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35096900-C42AC2A8-2198-4721-95F4-5376F16D166E
rank
NormalRank
type
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wasDerivedFrom
364e91b295599790022890905dfb6a8868a5a627
P2860
The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways.