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Q36281743-A25C7172-C5B8-4B5A-B681-ED3131023E0D
Q36281743-A25C7172-C5B8-4B5A-B681-ED3131023E0D
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Statement
http://www.wikidata.org/entity/statement/Q36281743-A25C7172-C5B8-4B5A-B681-ED3131023E0D
Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization.
P2860
Q36281743-A25C7172-C5B8-4B5A-B681-ED3131023E0D
BestRank
Statement
http://www.wikidata.org/entity/statement/Q36281743-A25C7172-C5B8-4B5A-B681-ED3131023E0D
rank
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type
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wasDerivedFrom
4165b805ca15815b4b8c1370b59402a9b098ead1
P2860
Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops.