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Q36534393-D5D6101E-3DB6-45C8-A8D8-12D02A301863
Q36534393-D5D6101E-3DB6-45C8-A8D8-12D02A301863
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Statement
http://www.wikidata.org/entity/statement/Q36534393-D5D6101E-3DB6-45C8-A8D8-12D02A301863
Correctors of ΔF508 CFTR restore global conformational maturation without thermally stabilizing the mutant protein.
P2860
Q36534393-D5D6101E-3DB6-45C8-A8D8-12D02A301863
BestRank
Statement
http://www.wikidata.org/entity/statement/Q36534393-D5D6101E-3DB6-45C8-A8D8-12D02A301863
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wasDerivedFrom
9e6b2250a959f605f6b0613f506edc99bbd22d43
P2860
Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops.