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Q37412499-7E23FB1A-64EF-41E4-8DF5-C0E8B637AFAF
Q37412499-7E23FB1A-64EF-41E4-8DF5-C0E8B637AFAF
BestRank
Statement
http://www.wikidata.org/entity/statement/Q37412499-7E23FB1A-64EF-41E4-8DF5-C0E8B637AFAF
MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL.
P2860
Q37412499-7E23FB1A-64EF-41E4-8DF5-C0E8B637AFAF
BestRank
Statement
http://www.wikidata.org/entity/statement/Q37412499-7E23FB1A-64EF-41E4-8DF5-C0E8B637AFAF
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type
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Statement
wasDerivedFrom
ebcbcded849f0d06f10cc4b9ffea81ac37108af6
P2860
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax).