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Q38947009-3302AC42-7349-47C3-A07D-98494FBFDE05
Q38947009-3302AC42-7349-47C3-A07D-98494FBFDE05
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38947009-3302AC42-7349-47C3-A07D-98494FBFDE05
A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1.
P2860
Q38947009-3302AC42-7349-47C3-A07D-98494FBFDE05
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38947009-3302AC42-7349-47C3-A07D-98494FBFDE05
rank
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type
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wasDerivedFrom
5bf4bff310a4e0832ff6080c0a567756e1f8d8c5
P2860
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.