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Q39373589-38BF2BCC-8661-40AF-838C-F6DF758D31F8
Q39373589-38BF2BCC-8661-40AF-838C-F6DF758D31F8
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39373589-38BF2BCC-8661-40AF-838C-F6DF758D31F8
The feasibility of enzyme targeted activation for amino acid/dipeptide monoester prodrugs of floxuridine; cathepsin D as a potential targeted enzyme.
P2860
Q39373589-38BF2BCC-8661-40AF-838C-F6DF758D31F8
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39373589-38BF2BCC-8661-40AF-838C-F6DF758D31F8
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wasDerivedFrom
f71e907ba18fb6a6fc5305eb4c8e0c3a5b6f9347
P2860
The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action.