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Q39571798-47FE48EF-A21E-491B-AE0F-152A488A09FB
Q39571798-47FE48EF-A21E-491B-AE0F-152A488A09FB
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39571798-47FE48EF-A21E-491B-AE0F-152A488A09FB
The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.
P2860
Q39571798-47FE48EF-A21E-491B-AE0F-152A488A09FB
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39571798-47FE48EF-A21E-491B-AE0F-152A488A09FB
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wasDerivedFrom
e3ccfdad84fd2939eb0a2c414818f3bc5646414d
P2860
The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity.