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Q42249160-A1852CF7-AC32-4BAD-95EE-9CCEEEFE7856
Q42249160-A1852CF7-AC32-4BAD-95EE-9CCEEEFE7856
BestRank
Statement
http://www.wikidata.org/entity/statement/Q42249160-A1852CF7-AC32-4BAD-95EE-9CCEEEFE7856
TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma.
P2860
Q42249160-A1852CF7-AC32-4BAD-95EE-9CCEEEFE7856
BestRank
Statement
http://www.wikidata.org/entity/statement/Q42249160-A1852CF7-AC32-4BAD-95EE-9CCEEEFE7856
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wasDerivedFrom
1522a67968b556516f4e4c5a1d6820dbdba5d043
P2860
The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype.