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1
Q47214928-3584FC2F-BB1C-4F7B-BB21-99B08A50A702
Q47214928-3584FC2F-BB1C-4F7B-BB21-99B08A50A702
BestRank
Statement
http://www.wikidata.org/entity/statement/Q47214928-3584FC2F-BB1C-4F7B-BB21-99B08A50A702
Partial rescue of F508del-CFTR channel gating with modest improvement of protein processing, but not stability by a dual-acting small molecule.
P2860
Q47214928-3584FC2F-BB1C-4F7B-BB21-99B08A50A702
BestRank
Statement
http://www.wikidata.org/entity/statement/Q47214928-3584FC2F-BB1C-4F7B-BB21-99B08A50A702
rank
NormalRank
type
BestRank
Statement
wasDerivedFrom
d1ab38966674cddc5f85eb5da5d7436e414cfd7f
P2860
Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops.