about
P688
C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survivalNovel role of PKR in inflammasome activation and HMGB1 releaseASC directs NF-kappaB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactionsDifferential activation of the inflammasome by caspase-1 adaptors ASC and IpafInhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptorNon-canonical inflammasome activation targets caspase-11Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificityFundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell deathThe Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretionInflammasome-mediated dysbiosis regulates progression of NAFLD and obesityA bacterial invasin induces macrophage apoptosis by binding directly to ICEAltered cytokine production in mice lacking P2X(7) receptorsPhosphorylation of NLRC4 is critical for inflammasome activationNalp1b controls mouse macrophage susceptibility to anthrax lethal toxinIntracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammationCellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophagesP2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophageSyk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization.Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.SERPINB1-mediated checkpoint of inflammatory caspase activation
P921
Q24291845-08CE1549-347F-42F6-813D-E75E4DD3E658Q24293509-3E541C63-4BBB-44BE-9AE7-CDA1CA931989Q24313497-4AB3A58D-0626-44DF-BBF5-A22ED989440EQ28266417-44F7BFEC-8CA7-4DD0-9738-21E28FA2B136Q28504668-F26D8321-0AB5-47D6-814A-2C400111281BQ28506831-DB5D9A65-D64D-4678-84FB-248EBB1E3918Q28508255-9D0BC48D-0B46-4504-B41A-4F2A22DB3846Q28509129-23149A50-F30A-4265-9AD1-DB533BF39E5FQ28512341-382A8645-9DD1-4D10-BEA1-D2FBB05DDB1DQ28512429-F60A78AB-B18C-4B34-9E89-519840BA1231Q28512778-24AD3B21-885F-47F8-8C0F-AD32EABD4438Q28512900-B347F8BD-E2D8-4EEA-ACD9-56CB1FDEE0F0Q28586061-D37CA3FF-D9EC-4358-9DC9-DAB8309393DAQ28586109-71B1D1E8-B9B7-49FA-92CD-48D3C171B790Q28586508-A05E8B6A-BC5F-46E4-BF7B-B684B9C2FC2AQ28591187-3CD8C7DC-7A5C-48A3-B1B9-8D53AECE42C2Q28591380-0C278DD4-53F2-4EE6-B815-B5D5A2D60BD7Q28593664-AFA78D20-8C64-486A-982C-FF87BB8AC067Q30668616-59AB08FC-A76A-4547-A237-60BBDF7DB077Q36267045-19E559AA-9F28-4DA2-847F-C932669485B3Q63345286-9739EB5E-133A-4BA3-A5BA-0D15B2C4E47B
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Caspase 1
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Caspase 1
@en
type
label
Caspase 1
@en
altLabel
CASP-1
@en
Casp1
@en
ICE
@en
IL-1 beta-converting enzyme
@en
IL-1B converting enzyme
@en
IL-1BC
@en
caspase-1
@en
interleukin-1 beta convertase
@en
interleukin-1 beta-converting enzyme
@en
p45
@en
prefLabel
Caspase 1
@en
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ENSMUSP00000027015