about
P688
Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoAThe mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposureThe Rho target PRK2 regulates apical junction formation in human bronchial epithelial cellsRegulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formationMammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitiveSOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS modelA novel FERM domain including guanine nucleotide exchange factor is involved in Rac signaling and regulates neurite remodelingThe adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)miceHuman neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2Affixin activates Rac1 via betaPIX in C2C12 myoblastACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activityExternal push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membraneThe LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migrationTiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neuronsFibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowthOncogene ect2 is related to regulators of small GTP-binding proteinsRac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation developmentLoss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targetingFERM domain containing protein 7 interacts with the Rho GDP dissociation inhibitor and specifically activates Rac1 signalingRac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neuronsWAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motilityBreast cancer-associated gene 3 (BCA3) is a novel Rac1-interacting proteinInvolvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microgliaIQGAP3 regulates cell proliferation through the Ras/ERK signalling cascadeLamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathwaysThe Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activityMerlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivoLocal phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.Wnt5a regulates midbrain dopaminergic axon growth and guidanceRho-GTPase-activating protein interacting with Cdc-42-interacting protein 4 homolog 2 (Rich2): a new Ras-related C3 botulinum toxin substrate 1 (Rac1) GTPase-activating protein that controls dendritic spine morphogenesisPak1 is involved in dendrite initiation as a downstream effector of Rac1 in cortical neuronsLis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrainSmall GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formationRac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneuronsHyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responsesVav GEFs are required for beta2 integrin-dependent functions of neutrophils.
P921
Q22253269-3D17960E-5356-4E14-92DA-A161368B9C1FQ24290129-6DE99157-5D3C-4323-B3BC-AAA40FDB231EQ24301517-0BBA989C-3CDA-4DFE-AD51-D0A21E5E5050Q24304376-25E00AA7-6E19-4C6E-BB6D-7D81F0DA22E4Q24304483-9D531808-67AF-4B92-AA6B-0AE9F93D8BC1Q24306328-C5032911-5BC4-40E2-B2AE-AAD101299738Q24307703-E6651D75-3FD7-40B3-924F-FE7D88B9D790Q24307819-D9CC0407-E705-435C-A052-42E0003F6BF3Q24314920-E12AE6CA-E754-47AF-8997-B6B0265D5411Q24316954-65C0FCD0-0221-449D-816F-B669296300B5Q24321686-44D7EAAB-98A3-4390-8149-146143B246B4Q24322612-88EB6F9C-EAA4-4C05-AD13-283C596C906EQ24339419-AB84F6F9-D86F-4BDD-8FF7-21AD825F37BCQ24678443-FADA862F-CA1D-4C93-B08A-705BE3E95A38Q28116790-34B830DA-556C-4E57-A46A-5213B89F14ABQ28211919-59067439-95DE-4731-9257-4E37079C7030Q28267723-F5D20DA9-7F5E-4B6B-9FAD-57B8AE3AAAA0Q28506302-6540F364-075E-44F6-895E-874691173412Q28506616-BF4F9979-54E6-4436-AA34-7B0B4C564B8FQ28506649-A3FF8745-6A7A-47E1-86C4-3C98ED3D21A5Q28506696-457CE0DA-AC69-44F9-B4A4-D13D45D23709Q28507062-2D72C500-6A30-4CF3-9619-A382B4C3A703Q28508172-0DE4C51B-3120-451F-A8A8-BDF172321C73Q28508347-37D58420-8656-42FB-8A2F-5A5610FA5A54Q28510385-FFB8E5D4-3146-4507-AE74-7CB4CF6D8B93Q28511099-CE411BD5-33FA-4A77-B67D-D99899CE0100Q28513141-2222E672-37F6-467A-B1F7-1A446969CAAEQ28513718-31BE0416-0128-40A1-BC4D-6F723986DAD3Q28513819-204F5DBD-1DEF-49D1-8BE7-A1D38A509A04Q28567890-D084C0E0-E025-44FE-BA0B-906BDC353C8BQ28568522-E09EA0F2-805D-46EE-B49B-202C5DD0BD94Q28584909-AF206B2F-9093-4BBD-82DF-BF4154DAC30DQ28585273-2F9CC8E5-933C-4D8A-B7BC-5D215D93B8AFQ28585571-5D366B1F-70A0-4F31-9277-01D539A7AA13Q28585865-52A17013-1003-4A97-A423-A35AA62A2645Q28587366-B67A3DFF-2024-47F4-908E-8617D1864BCCQ28588387-7F23450D-488B-46D6-BB01-2350C44A4F89Q28588648-3CE29EEE-8C1A-43D4-92FD-CAF963E3424CQ28589110-B40C0B0F-2AFD-4502-9D68-0A45819F5D6DQ28590406-396E3896-36B2-426C-9ACE-699362C6D60F
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Rac family small GTPase 1
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Rac family small GTPase 1
@en
type
label
Rac family small GTPase 1
@en
altLabel
RAS-related C3 botulinum substrate 1
@en
Rac1
@en
p21-Rac1
@en
ras-related C3 botulinum toxin substrate 1
@en
prefLabel
Rac family small GTPase 1
@en
P361
P680
P681
P682
P352
P31
P352
P637
NP_001334459
P680
P681
P682
P702
P703
P705
ENSMUSP00000079380
ENSMUSP00000098058