Insulin like growth factor 1 receptor

Insulin like growth factor 1 receptor

Item
http://www.wikidata.org/entity/Q2005209
IGF1R
P688
Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domainIntracellular association of a mutant insulin-like growth factor receptor with endogenous receptorsRegulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblastsType 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1)Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblastsInsulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involvedNon-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptorInteraction of the alpha beta dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylationThe direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signalingDistinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functionsAutoinhibition of the insulin-like growth factor I receptor by the juxtamembrane regionPurified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinityRole of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3)Focal adhesion kinase (FAK) activates and stabilizes IGF-1 receptorInsulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}Involvement of insulin-like growth factor 1 receptor signaling in the amyloid-β peptide oligomers-induced p75 neurotrophin receptor protein expression in mouse hippocampus.Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity.Fine details of IGF-1R activation, inhibition, and asymmetry determined by associated hydrogen /deuterium-exchange and peptide mass mapping.Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I
P921

Insulin like growth factor 1 receptor

Item
http://www.wikidata.org/entity/Q2005209
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Insulin like growth factor 1 receptor
@en
Insulin like growth factor 1 receptor
@nl
Receptor insulinu sličnog faktora rasta 1
@sh
Receptor insulinu sličnog faktora rasta 1
@sr
Receptor insulinu sličnog faktora rasta 1
@sr-el
Рецептор инсулину сличног фактора раста 1
@sr-ec
胰岛素样生长因子1受体
@zh
type
label
Insulin like growth factor 1 receptor
@en
Insulin like growth factor 1 receptor
@nl
Receptor insulinu sličnog faktora rasta 1
@sh
Receptor insulinu sličnog faktora rasta 1
@sr
Receptor insulinu sličnog faktora rasta 1
@sr-el
Рецептор инсулину сличног фактора раста 1
@sr-ec
胰岛素样生长因子1受体
@zh
altLabel
CD221
@sr
IGF-I receptor
@en
IGF1R
@en
IGF1R
@sr
IGFIR
@sr
IGFR
@sr
Insulin-like growth factor I receptor
@en
JTK13
@sr
insulin-like growth factor 1 receptor
@en
soluble IGF1R variant 1
@en
prefLabel
Insulin like growth factor 1 receptor
@en
Insulin like growth factor 1 receptor
@nl
Receptor insulinu sličnog faktora rasta 1
@sh
Receptor insulinu sličnog faktora rasta 1
@sr
Receptor insulinu sličnog faktora rasta 1
@sr-el
Рецептор инсулину сличног фактора раста 1
@sr-ec
胰岛素样生长因子1受体
@zh
P129
P31
P352
P361
P527
P637
P638
P680
P681
P682
P692
P702
P703
P705
P352
P637
P638
P129
P31
P352
P361
P527
P637
P638
P680
P681
P682
P692
P702
P703
P705