about
P688
The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia proteinICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formationRecognition of multivalent histone states associated with heterochromatin by UHRF1 proteinICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domainNucleosome-interacting proteins regulated by DNA and histone methylationThe USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expressionUHRF1 plays a role in maintaining DNA methylation in mammalian cellsICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression
P921
Q24297944-C0737E6B-608B-48B0-9010-3CBFF11B6145Q24298944-80BB3A6F-4AED-4E8E-8A1D-8408137166F4Q24299712-25E255DE-6996-46DB-B0CA-9F90C4595595Q24303631-DAC1A55C-7C74-48A3-943F-926E43FAE590Q24304841-12B64A5B-70D1-4301-916F-F556BADA8616Q24313017-0CC144CF-F3A9-48CD-8485-5C11DB86AEBEQ24315922-D88BADAC-B41C-4228-A335-CE2FD295F678Q24336152-BF2E16D1-56AC-4FD5-BF4C-8A82DA138BD9Q28119015-957DEE8B-AA3C-43E7-A483-E9CE39CA7870
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Ubiquitin like with PHD and ring finger domains 1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Ubiquitin like with PHD and ring finger domains 1
@en
Ubiquitin like with PHD and ring finger domains 1
@nl
type
label
Ubiquitin like with PHD and ring finger domains 1
@en
Ubiquitin like with PHD and ring finger domains 1
@nl
altLabel
E3 ubiquitin-protein ligase UHRF1
@en
HuNp95
@en
RING finger protein 106
@en
RING-type E3 ubiquitin transferase UHRF1
@en
UHRF1
@en
Ubiquitin-like-containing PHD and RING finger domains protein 1
@en
hNp95
@en
hUHRF1
@en
inverted CCAAT box-binding protein of 90 kDa
@en
nuclear phosphoprotein 95
@en
prefLabel
Ubiquitin like with PHD and ring finger domains 1
@en
Ubiquitin like with PHD and ring finger domains 1
@nl
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ENSP00000478171
ENSP00000478348
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ENSP00000484739
ENSP00000485604
ENSP00000498698