OPA1 mitochondrial dynamin like GTPase

OPA1 mitochondrial dynamin like GTPase

Item
http://www.wikidata.org/entity/Q21106682
OPA1
P688
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization, and effect on mitochondrial morphologyOPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypesMitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescenceThe BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanismsMff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cellsThe E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMODifferential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondriaLoss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosisOPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulationA Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.
P921

OPA1 mitochondrial dynamin like GTPase

Item
http://www.wikidata.org/entity/Q21106682
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in OPA1, mitochondrial dynamin like GTPase
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
OPA1 mitochondrial dynamin like GTPase
@en
OPA1 mitochondrial dynamin like GTPase
@nl
type
label
OPA1 mitochondrial dynamin like GTPase
@en
OPA1 mitochondrial dynamin like GTPase
@nl
altLabel
OPA1
@en
dynamin-like 120 kDa protein, mitochondrial
@en
dynamin-like guanosine triphosphatase
@en
mitochondrial dynamin-like GTPase
@en
optic atrophy 1 (autosomal dominant)
@en
optic atrophy protein 1
@en
prefLabel
OPA1 mitochondrial dynamin like GTPase
@en
OPA1 mitochondrial dynamin like GTPase
@nl
P31
P352
P361
P527
P637
P680
P681
P682
P702
P703
P705
P7260
P352
P637
P31
P352
P361
P527
P637
P680
P681
P682
P702
P703
P705
P7260