Retinoblastomov%C3%BD_proteinRB1Retinoblastom-ProteinRetinoblastoma_proteinProte%C3%ADna_del_retinoblastomaProt%C3%A9ine_du_r%C3%A9tinoblastomePRbProteina_del_retinoblastomaRb%E9%81%BA%E4%BC%9D%E5%AD%90RB1%D0%91%D0%B5%D0%BB%D0%BE%D0%BA_%D1%80%D0%B5%D1%82%D0%B8%D0%BD%D0%BE%D0%B1%D0%BB%D0%B0%D1%81%D1%82%D0%BE%D0%BC%D1%8BRetinoblastomproteinRetinoblastoma_proteinRB_(%D0%B1%D1%96%D0%BB%D0%BE%D0%BA)Q21111463%E8%A7%86%E7%BD%91%E8%86%9C%E6%AF%8D%E7%BB%86%E8%83%9E%E7%98%A4%E8%9B%8B%E7%99%BD
about
RB1:E2F1;E2F2;E2F3:TFDP1;TFDP2:Cyclin E:p-T160-CDK2:RB1RB1:RNA primer-DNA primer:origin duplex with DNA damagep-FZR1;p-RB1Condensin II:RB1RUNX2:RB1Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexesAssociation of Rb with Cyclin E:Cdk2 complexesRB1 binds condensin IIE2F1/E2F2/E2F3 and SP1 stimulate transcription of p14-ARF mRNASAHF formationRUNX2 binds RB1RB1 binds and inhibits E2F1/2/3:DP1/2 complexes
P527
P688
Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of RbRBP95, a novel leucine zipper protein, binds to the retinoblastoma proteinThe retinoblastoma family proteins bind to and activate diacylglycerol kinase zetaInduction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factorsStructure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F releaseThe retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activityProhibitin requires Brg-1 and Brm for the repression of E2F and cell growth.L3MBTL1, a histone-methylation-dependent chromatin lockHMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalphaRegulation of Rb gene expression by an MBD2-interacting zinc finger protein MIZF during myogenic differentiationThe chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4aARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathwaysLoss of pRB causes centromere dysfunction and chromosomal instabilityOncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4aThe promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma proteinIdentification of discrete structural domains in the retinoblastoma protein. Amino-terminal domain is required for its oligomerizationStructural basis for the specificity of bipartite nuclear localization sequence binding by importin-alphaPhysical interaction between pRb and cdk9/cyclinT2 complexPost-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cellsStructural and functional characterization of the HPV16 E7 protein expressed in bacteriaHomology between a region of the human retinoblastoma gene and L1 family repetitive sequencesMiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neuronsHaploinsufficiency of the retinoblastoma protein gene reduces diet-induced obesity, insulin resistance, and hepatosteatosis in mice.
P921
Q50250812-088FAFBF-2C93-4735-9179-28EDF5EFDA3AQ50250872-B2908BB3-F60E-4CF9-920B-81C2CE185BA6Q50250923-60E1284A-89E1-4E61-A3FD-E0ADB05D4043Q50250947-44FEF309-F2A9-42C9-89B7-373E2C6FC2ABQ50251241-EC305A7C-11F7-486E-972F-E220985BB661Q50258476-EF5369F6-9271-45EC-95D9-8FBAEFEA4C7EQ50285971-CE5C0D15-DBE2-4CFE-AB9A-28E1AA9659F8Q50286002-0DFEA83F-B1B0-4599-8D6C-1EB042980E11Q50286194-7662FFD1-B866-49F4-A1FA-B9F373269879Q50286650-C049A39F-817D-41DE-808D-186A95F6698CQ50286949-CF3A05A8-3390-4816-A144-97D42A7919C1Q50290681-F494FBBE-05A1-4721-A064-C3D2AA131CCBQ55195011-D0F9A8DE-B26E-45A9-9339-0EFA184B5768
P527
Q22008567-F254480F-2F03-48B4-AECF-A87B926E0DCBQ22253992-AAD60AC6-EFFC-4EEB-8F60-3AE3A0947550Q24289568-5C0E2D16-2AF9-4916-BA3F-FE2996A429B3Q24294841-62583F42-69E5-4108-A2A6-7944486306C5Q24296947-CB938F0F-8E01-4C1F-89C1-E7076772663FQ24299116-FD1419DD-3978-4B4C-8B20-5539053ED59CQ24299515-8030E6C6-F1C1-4C8A-838D-7BE1A63FA647Q24299737-EB042872-0271-45FF-9F79-800FCBD6F5B4Q24307503-7CAB2F87-7765-44A0-B683-D5379C027A48Q24311673-4BF22DA3-2EA2-41B7-9BBA-91C6104B0C1CQ24314495-8D07B483-1BC1-4E2D-A065-A26C419A93EEQ24317334-B9048FF9-F512-4CC8-BE80-58FF0552EE91Q24321528-CA88E337-4D82-41DB-B7CA-A1A26ADD2148Q24321598-BD906930-C941-4812-A09E-1BE1D519F2C7Q24324559-BDAC267C-6FC9-48E3-A457-D22AB784CC54Q24324766-A6C81C7C-EEA1-4643-92A9-899078ABF407Q24336303-092D6F1D-D0DB-4182-A0F2-00E5964D4872Q27640986-DD40C299-E08B-434D-83FE-3BCC54F2EA93Q28114798-8DDA0E2C-59FB-402D-BE13-CD3EAA0D3E53Q28118300-344D71E0-34EC-4180-9FEC-37F0BDD17CC2Q28910451-AB652700-9916-4E0E-8AD6-3878AC1B6DD0Q28910466-D3096462-3E19-4A73-8E06-40D1CE04B1E7Q37261417-0009C08D-2C73-4F79-B0E8-3F1A42A2AEA8Q46024728-9B8F0B89-1043-4803-8810-D145871DA2D8
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in RB transcriptional corepressor 1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
PRb
@id
Proteina del retinoblastoma
@it
Proteína del retinoblastoma
@es
Protéine du rétinoblastome
@fr
RB (білок)
@uk
RB transcriptional corepressor 1
@en
RB1
@cy
RB1
@pl
Rb遺伝子
@ja
Retinoblastom-Protein
@de
type
label
PRb
@id
Proteina del retinoblastoma
@it
Proteína del retinoblastoma
@es
Protéine du rétinoblastome
@fr
RB (білок)
@uk
RB transcriptional corepressor 1
@en
RB1
@cy
RB1
@pl
Rb遺伝子
@ja
Retinoblastom-Protein
@de
altLabel
GOS563 exon 17 substitution mutation causes premature stop
@en
RB1
@en
Rb
@en
exon 17 tumor GOS561 substitution mutation causes premature stop
@en
p105-Rb
@en
pRb
@en
pp110
@en
prepro-retinoblastoma-associated protein
@en
protein phosphatase 1, regulatory subunit 130
@en
retinoblastoma 1
@en
prefLabel
PRb
@id
Proteina del retinoblastoma
@it
Proteína del retinoblastoma
@es
Protéine du rétinoblastome
@fr
RB (білок)
@uk
RB transcriptional corepressor 1
@en
RB1
@cy
RB1
@pl
Rb遺伝子
@ja
Retinoblastom-Protein
@de
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2776062698
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XP_011533473
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ENSP00000267163
ENSP00000434702
ENSP00000496005
ENSP00000496556
ENSP00000497193