about
P688
Role of LXRs in control of lipogenesisRegulation of LPCAT3 by LXRActivation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cellsFGF-1 induces expression of LXRalpha and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytesInduction of transglutaminase 2 by a liver X receptor/retinoic acid receptor alpha pathway increases the clearance of apoptotic cells by human macrophagesThe nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophagesLXR, a nuclear receptor that defines a distinct retinoid response pathwayCCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylaseLiver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophagesLiver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDLSelective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterolMolecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRsBoth liver-X receptor (LXR) isoforms control energy expenditure by regulating brown adipose tissue activity.GPS2 is required for cholesterol efflux by triggering histone demethylation, LXR recruitment, and coregulator assembly at the ABCG1 locus.
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Nuclear receptor subfamily 1 group H member 3
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Nuclear receptor subfamily 1 group H member 3
@en
Nuclear receptor subfamily 1 group H member 3
@nl
type
label
Nuclear receptor subfamily 1 group H member 3
@en
Nuclear receptor subfamily 1 group H member 3
@nl
altLabel
Liver X receptor alpha
@en
NR1H3
@en
liver X nuclear receptor alpha variant 1
@en
oxysterols receptor LXR-alpha
@en
prefLabel
Nuclear receptor subfamily 1 group H member 3
@en
Nuclear receptor subfamily 1 group H member 3
@nl
P361
P637
P638
P680
P681
P682
P705
P352
P637
P31
P352
P637
NP_001123573
NP_001123574
NP_001238863
NP_001238864
NP_001350524
XP_005252763
XP_005252770
XP_005252775
XP_011518107
P638
P680
P681
P682
P702
P703
P705
ENSP00000378793
ENSP00000384745
ENSP00000385073
ENSP00000385801
ENSP00000387946
ENSP00000391005
ENSP00000396132
ENSP00000403696
ENSP00000403798
ENSP00000406692