about
P527
P688
Orai1 and STIM reconstitute store-operated calcium channel functionLarge store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1Atomic force microscopy (AFM) imaging suggests that stromal interaction molecule 1 (STIM1) binds to Orai1 with sixfold symmetryOrai1 is an essential pore subunit of the CRAC channelUbiquilin 1 interacts with Orai1 to regulate calcium mobilizationSTIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entryAmplification of CRAC current by STIM1 and CRACM1 (Orai1)Mitochondria control store-operated Ca2+ entry through Na+ and redox signals.Pore architecture of the ORAI1 store-operated calcium channel.Functional stoichiometry of the unitary calcium-release-activated calcium channelStructural determinants of ion permeation in CRAC channels.Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8Calsequestrin-1 Regulates Store-Operated Ca2+ Entry by Inhibiting STIM1 Aggregation.Direct Binding Between Orai1 and AC8 Mediates Dynamic Interplay Between Ca2+ and cAMP SignalingMolecular understanding of calcium permeation through the open Orai channel
P921
Q24293232-6746173D-2E83-489B-B811-A4CBF2740F56Q24294877-899B8A79-8471-4376-822A-490C123CD333Q24300302-663C72E9-0B15-4452-A722-7E82D041838BQ24300383-3E722664-6F3A-4794-9923-630E596C5D75Q24308010-9CCB862C-F0F9-4415-A1DD-13CAEB35960DQ24315782-C9836718-38A2-4622-8A59-8884462A1B09Q24322017-BE14D1E8-3C92-4208-A47D-4D2739ADDE9DQ24338326-DD7EA902-8A60-4938-A622-8FAE5E33BB91Q30274638-35BEDFBD-571A-4915-AB58-15007CDB9F79Q33739944-95AB4756-D148-471D-84A4-8E3C7B2CB78CQ36870049-D651AB99-99E2-4DB3-9E67-664BD9EDF7EDQ37471832-17931BD0-A9E1-4101-AC45-7AB68741713FQ39890552-367F9132-75CF-4485-A421-9005E13EB4B3Q42428344-AE44B4C5-EEBA-425A-AEFF-3F98C0666365Q62001063-30B3F4C8-3AFB-4C55-AA06-ED66BE6538F0Q64099379-5C793079-FE10-4C83-B9DA-FAF3C3D3093F
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in ORAI calcium release-activated calcium modulator 1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
ORAI calcium release-activated calcium modulator 1
@en
type
label
ORAI calcium release-activated calcium modulator 1
@en
altLabel
ORAI1
@en
calcium release-activated calcium channel protein 1
@en
calcium release-activated calcium modulator 1
@en
protein orai-1
@en
transmembrane protein 142A
@en
prefLabel
ORAI calcium release-activated calcium modulator 1
@en
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1.A.52.1.1