P688
Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibitionThe Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Müllerian-inhibiting substance, and the androgen receptorYAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesisWT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosisDevelopmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimesterPINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expressionWT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivoBASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin geneUpregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumorsExpression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell linesInhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2Membranoproliferative glomerulonephritis associated with a mutation in Wilms' tumour suppressor gene 1Why zinc fingers prefer zinc: ligand-field symmetry and the hidden thermodynamics of metal ion selectivityRegulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumorsWT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosisHigh affinity binding sites for the Wilms' tumour suppressor protein WT1Repression of Pax-2 by WT1 during normal kidney developmentThe WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressorCharacterization of the zinc finger protein encoded by the WT1 Wilms' tumor locusDynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiationThe Wilms' tumor suppressor gene WT1 is negatively autoregulatedTranscriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoterNuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissuesHuman platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequenceControl of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A.
P921
Q22003911-FC5E886D-3339-4686-A400-B5754B2C0F9EQ22008005-B8E7349C-18FB-4F66-805E-F8881DFBA325Q22009123-20EE6D7A-2C56-4D44-8183-18181F7FDB29Q24292676-5B590C91-ED46-4801-9397-A4100372216AQ24293254-FD35C505-A12C-4B29-A8E3-23100FF06AECQ24296236-593A8A9F-0AFA-4F33-94AE-A60D33C6C77CQ24300741-D03383F5-3516-48D2-B071-56E61309EFAAQ24303633-A15A726F-5612-4847-9F16-E31AB1C71FE1Q24304157-F1469720-F541-4319-AF21-FB665589CAF3Q24304875-668F7A17-862B-4623-BDED-78FF3D976505Q24305390-09A828AC-C5AD-4D8D-B093-681FD7DFD7CAQ24308507-F0EF46F6-CB30-4E0D-81DC-CFCAB1115409Q24309088-BFC224E8-D93F-4CDF-B7A2-3D4DF5166928Q24309645-BFF36D3D-74E1-48EA-BC5C-9C431BF9217BQ24310274-8065543C-3819-4CFA-989D-420B41BE1F36Q24313334-9D915783-015F-4CFE-BA74-DC3BDBD164F9Q24313408-DB0730E2-8F5F-46C5-86B0-8B4EDAD9BF53Q24313596-02BA345B-358C-4C70-9256-C381DA84AE27Q24314245-28C82C98-C178-4D83-91ED-B6FF45BC7A06Q24314726-3DB2AE99-A145-44A5-A93D-E589B01951FCQ24316544-CDCEB758-61B0-4DD2-92EC-38EC55370BD6Q24318947-5A0E2DDE-E748-4489-9C88-414F07E1A3F3Q24320712-9522D949-8572-4342-AAC7-70CFF99D2FCAQ24336026-A59AAC32-E8C8-4F75-8FE9-B8513F8F31C5Q24336835-3BCCFFB8-EB05-4B95-8670-D1C19469B754Q24337260-F304A18B-7D65-47E0-98A2-54E36C3EDCA6Q24337538-30AC9464-A04E-439F-9944-FBA9F8CE21BAQ28117086-8B0E7C0B-DAA9-41C4-8070-376E662E045CQ39264413-4C369A1D-485C-465F-9B79-7F6081DBD25E
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in Wilms tumor 1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
WT1 transcription factor
@en
WT1 transcription factor
@nl
WT1
@cs
WT1
@cy
WT1
@fa
WT1
@uk
Wilms-Tumor-Protein
@de
腎芽腫蛋白
@zh
type
label
WT1 transcription factor
@en
WT1 transcription factor
@nl
WT1
@cs
WT1
@cy
WT1
@fa
WT1
@uk
Wilms-Tumor-Protein
@de
腎芽腫蛋白
@zh
altLabel
WT1
@en
WT33
@en
Wilms tumor 1
@en
Wilms tumor protein isoform Ex4a(+)
@en
Wilms tumor protein
@en
prefLabel
WT1 transcription factor
@en
WT1 transcription factor
@nl
WT1
@cs
WT1
@cy
WT1
@fa
WT1
@uk
Wilms-Tumor-Protein
@de
腎芽腫蛋白
@zh
P637
P638
P680
P681
P682
P705
P352
P31
P352
P637
NP_001185480
NP_001185481
NP_001354783
P638
P680
P682
P702
P703
P705
ENSP00000331327
ENSP00000368368
ENSP00000368370
ENSP00000413452
ENSP00000415516
ENSP00000435307
ENSP00000435624
ENSP00000491984
ENSP00000492269
ENSP00000498574