about
P527
P688
A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2bSPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 productionIntramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidaseRegulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2bThe α-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b)In vivo measurements of ethanol concentration in rabbit brain by 1H magnetic resonance spectroscopyConsensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilinsDifferential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysisSignal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail
P921
Q24296642-69C57F38-2897-4DC3-B574-E43C8368D939Q24296666-8E847909-ABBE-4CD0-8EB2-91CB24DF8FB3Q24298275-5EAD1DAD-6A63-4706-BB94-42EBC640506BQ24298773-46C4626B-FF98-48EB-AA6F-68C234E5A71EQ24300479-CEC3E688-B032-4676-9E02-1039944E7E5EQ24302452-15B61701-C8E7-4F4D-ABB0-FEC831D2AE95Q24305015-B1BCBF28-8A8B-4DF8-AC60-35DD6D6FB990Q24306785-45B62553-FA84-45E3-8036-B08283B37AD7Q24311748-5EAE0A5B-7663-4BE2-A2F2-58F790A5ADB3Q24337321-90D7BAA0-49DF-4642-9B85-27B589CD9D08
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in Signal peptide peptidase like 2B
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Signal peptide peptidase like 2B
@en
type
label
Signal peptide peptidase like 2B
@en
altLabel
IMP-4
@en
PSH4
@en
SPP-like 2B
@en
SPPL2B
@en
intramembrane protease 4
@en
presenilin homologous protein 4
@en
presenilin-like protein 1
@en
signal peptide peptidase-like 2B
@en
prefLabel
Signal peptide peptidase like 2B
@en
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P527
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NP_001070706
XP_011526440
XP_011526441
XP_011526442
XP_016882505
XP_016882506
XP_016882507
XP_016882508
XP_024307387
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P681
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ENSP00000477658
ENSP00000478298
ENSP00000478510
ENSP00000480311
ENSP00000480813
ENSP00000482362
ENSP00000482470