Mechanisms of CFTR Folding at the Endoplasmic Reticulum

Mechanisms of CFTR Folding at the Endoplasmic Reticulum

Item
http://www.wikidata.org/entity/Q21129277
Correcting the cystic fibrosis disease mutant, A455E CFTRCodon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator.VX-809 corrects folding defects in cystic fibrosis transmembrane conductance regulator protein through action on membrane-spanning domain 1.Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infectionFrom CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.Restoration of NBD1 thermal stability is necessary and sufficient to correct ∆F508 CFTR folding and assemblyMapping the energy landscape for second-stage folding of a single membrane protein.Mechanism-based corrector combination restores ΔF508-CFTR folding and function.CFTR: A New Horizon in the Pathomechanism and Treatment of Pancreatitis.The safety dance: biophysics of membrane protein folding and misfolding in a cellular contextFrom the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking.Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells.Substitution of Yor1p NBD1 residues improves the thermal stability of Human Cystic Fibrosis Transmembrane Conductance Regulator.Genetic deletion of keratin 8 corrects the altered bone formation and osteopenia in a mouse model of cystic fibrosis.A minimal helical-hairpin motif provides molecular-level insights into misfolding and pharmacological rescue of CFTRPeripheral Protein Quality Control as a Novel Drug Target for CFTR Stabilizer
P2860

Mechanisms of CFTR Folding at the Endoplasmic Reticulum

Item
http://www.wikidata.org/entity/Q21129277
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@ast
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@en
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@en-gb
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@nl
type
label
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@ast
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@en
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@en-gb
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@nl
prefLabel
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@ast
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@en
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@en-gb
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Mechanisms of CFTR Folding at the Endoplasmic Reticulum
@en
P2093
P2860
P304
P31
P356
P407
P478
P577
P5875
P698
P921
P932