AIP4/Itch regulates Notch receptor degradation in the absence of ligand
about
The adaptor-associated kinase 1, AAK1, is a positive regulator of the Notch pathwayThe prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancerThe role of targeted protein degradation in early neural developmentThe Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch SignallingA perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis.Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesisEndocytosis and signalling: intertwining molecular networksTurn It Down a NotchSEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.Notch and the skeleton.Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease.Basal body proteins regulate Notch signaling through endosomal trafficking.Current views on the role of Notch signaling and the pathogenesis of human leukemia.Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.Integration of clearance mechanisms: the proteasome and autophagy.The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation.Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancerSu(dx) E3 ubiquitin ligase-dependent and -independent functions of polychaetoid, the Drosophila ZO-1 homologueA central role for Notch in effector CD8(+) T cell differentiationDrosophila Ndfip is a novel regulator of Notch signaling.Structural insights into the functional versatility of WW domain-containing oxidoreductase tumor suppressor.cir-ITCH plays an inhibitory role in colorectal cancer by regulating the Wnt/β-catenin pathway.Dual regulation of notch1 signaling pathway by adaptor protein fe65Identification of calgranulin B interacting proteins and network analysis in gastrointestinal cancer cells.Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase.Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.Notch Signaling and the Skeleton.Numb regulates post-endocytic trafficking and degradation of Notch1.Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells.The multiple facets of ubiquitination in the regulation of notch signaling pathway.Deubiquitinases in the regulation of NF-κB signaling.Regulation of NF-κB signaling by the A20 deubiquitinase.Regulation of NF-κB by deubiquitinases.Balanced ubiquitination determines cellular responsiveness to extracellular stimuli.Ubiquitinations in the notch signaling pathway.Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease.The E3 ligase Itch in immune regulation and beyond.Notch in fibrosis and as a target of anti-fibrotic therapy.Ubiquitination and the Regulation of Membrane Proteins.The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.
P2860
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P2860
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@ast
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@en
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@en-gb
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@nl
type
label
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@ast
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@en
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@en-gb
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@nl
altLabel
AIP4/Itch Regulates Notch Receptor Degradation in the Absence of Ligand
@en
prefLabel
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@ast
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@en
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@en-gb
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@nl
P2860
P3181
P1433
P1476
AIP4/Itch regulates Notch receptor degradation in the absence of ligand
@en
P2093
Alain Israël
Patricia Chastagner
P2860
P3181
P356
10.1371/JOURNAL.PONE.0002735
P407
P50
P577
2008-07-16T00:00:00Z