8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage
about
Long noncoding RNAs in cancer: mechanisms of action and technological advancementsEmergence and Evolution of Hominidae-Specific Coding and Noncoding Genomic Sequences.Mutation and Human Exceptionalism: Our Future Genetic LoadLineage-specific genomics: Frequent birth and death in the human genome: The human genome contains many lineage-specific elements created by both sequence and functional turnoverMassively parallel cis-regulatory analysis in the mammalian central nervous systemFinding needles in a genomic haystack: targeted capture identifies clear signatures of selection in a nonmodel plant species.A method for calculating probabilities of fitness consequences for point mutations across the human genomeHIPSTR and thousands of lncRNAs are heterogeneously expressed in human embryos, primordial germ cells and stable cell linesNegative selection in humans and fruit flies involves synergistic epistasis.Approaches for establishing the function of regulatory genetic variants involved in disease.Enhanced transcriptome maps from multiple mouse tissues reveal evolutionary constraint in gene expression.Enhancer evolution across 20 mammalian species.Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low DivergenceQuantification of GC-biased gene conversion in the human genome.Limits and patterns of cytomegalovirus genomic diversity in humans.The meaning of biological informationDetermining the Effect of Natural Selection on Linked Neutral Divergence across SpeciesFast, scalable prediction of deleterious noncoding variants from functional and population genomic data.Comparative Expression Dynamics of Intergenic Long Noncoding RNAs in the Genus Drosophila.Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordinationDynamics of genome size evolution in birds and mammalsPrinciples of miRNA-mRNA interactions: beyond sequence complementarity.Biological function in the twilight zone of sequence conservationWhen is it MODY? Challenges in the Interpretation of Sequence Variants in MODY Genes.The canine era: the rise of a biomedical model.CRISPR Screens to Discover Functional Noncoding Elements.Evolutionary clues in lncRNAs.Long non-coding RNAs in human early embryonic development and their potential in ART.Evolution of Local Mutation Rate and Its Determinants.Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations.Polymerase ζ Activity Is Linked to Replication Timing in Humans: Evidence from Mutational Signatures.The identification and functional annotation of RNA structures conserved in vertebrates.An Upper Limit on the Functional Fraction of the Human GenomeRBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts.Clinical use of sperm DNA fragmentation analysis results, a practical example of how to deal with too much information from the literature in reproductive medicine.Natural selection beyond genes: Identification and analyses of evolutionarily conserved elements in the genome of the collared flycatcher (Ficedula albicollis).History, Discovery, and Classification of lncRNAs.On causal roles and selected effects: our genome is mostly junk.Principles and methods of in-silico prioritization of non-coding regulatory variants.High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.
P2860
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P2860
8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
8.2% of the Human genome is co ...... t classes in the human lineage
@ast
8.2% of the Human genome is co ...... t classes in the human lineage
@en
8.2% of the Human genome is co ...... t classes in the human lineage
@en-gb
8.2% of the Human genome is co ...... t classes in the human lineage
@nl
type
label
8.2% of the Human genome is co ...... t classes in the human lineage
@ast
8.2% of the Human genome is co ...... t classes in the human lineage
@en
8.2% of the Human genome is co ...... t classes in the human lineage
@en-gb
8.2% of the Human genome is co ...... t classes in the human lineage
@nl
altLabel
8.2% of the Human Genome Is Co ...... t Classes in the Human Lineage
@en
prefLabel
8.2% of the Human genome is co ...... t classes in the human lineage
@ast
8.2% of the Human genome is co ...... t classes in the human lineage
@en
8.2% of the Human genome is co ...... t classes in the human lineage
@en-gb
8.2% of the Human genome is co ...... t classes in the human lineage
@nl
P2860
P50
P3181
P1433
P1476
8.2% of the Human genome is co ...... t classes in the human lineage
@en
P2093
Stephen Meader
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1004525
P407
P577
2014-07-01T00:00:00Z