about
P688
Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesisProapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alphaEssential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosisRegulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic functionA subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.Contribution of calumin to embryogenesis through participation in the endoplasmic reticulum-associated degradation activityTargeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetesPICK1, an anchoring protein that specifically targets protein kinase Calpha to mitochondria selectively upon serum stimulation in NIH 3T3 cellsSDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cellsAnks4b, a novel target of HNF4α protein, interacts with GRP78 protein and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cellsMice lacking the MHC class II-associated invariant chainUBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptorsThe mouse FKBP23 binds to BiP in ER and the binding of C-terminal domain is interrelated with Ca2+ concentrationGRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growthThe PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human β-cells and its targeted inactivation impairs glucose toleranceElevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegenerationUbiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosisVaspin is an adipokine ameliorating ER stress in obesity as a ligand for cell-surface GRP78/MTJ-1 complexEndoplasmic reticulum-associated degradation-induced dissociation of class II invariant chain complexes containing a glycosylation-deficient form of p41A novel type of co-chaperone mediates transmembrane recruitment of DnaK-like chaperones to ribosomesPresenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brainEditing-defective tRNA synthetase causes protein misfolding and neurodegenerationPresenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathwayGoofy coordinates the acuity of olfactory signalingSorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunitsLifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic CellsProgressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress.Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS modelSubstrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions.
P921
Q24292962-13787AE1-1C37-4DA3-A482-48C7280E58D6Q24322072-3EE13645-29A7-48CD-AACA-2045087B1FD0Q24323246-3D07AC48-A3D4-4F17-B9D2-C53DDDAD395CQ24324029-A989D110-594F-4454-85D1-1C28B4C6D219Q24338246-BA0AF004-2E9B-4336-91AD-B48B36766E8AQ24541564-5CA06A7B-9FCE-4842-8053-9EA6C9AF60FAQ28505255-65B5389B-AEF4-4C74-94FF-FF31E68AAD95Q28506402-7072FD98-429D-41EB-BA94-5AFA8B3DF21DQ28506600-814C1870-364D-44B8-B18E-DCAF2341EC4BQ28506686-3F817649-25CD-41AC-AC82-3A096F08D214Q28507247-ED5FF896-5525-4CB4-AAB2-1183D8DF5262Q28507606-DD2A264A-D7DE-4828-B203-5B0D9A0CE7CCQ28507709-EF11A609-B6FA-40C5-A231-771FFE4BBE44Q28507842-379D619F-CD88-4A69-9FC0-51A1761A0890Q28508324-9263864B-E5FB-4AA3-8BD8-C3D2F6984125Q28510300-02017C71-1D13-45AA-AFC2-513A832E17E0Q28512069-9DE1B22B-3037-4234-8450-76C389D34D06Q28574413-A65A9428-83F0-4218-805F-4D5B588AD45CQ28586654-276DACC3-C30C-4021-AFBB-473FD474F11DQ28588164-5C778364-3853-46F4-93D6-A273B53CA638Q28588605-18402A1E-5AEF-4128-B53E-796BDF1CB22DQ28589919-9C620E93-45A4-4B27-94A9-3D07B365D1A7Q28590188-FAC32E25-CF9B-401F-959A-75E4A63D74FEQ28591202-86ACE0E6-D459-4CBE-9395-28581030995FQ28593697-0A089292-F9F2-4D7D-B17F-C7CBC8ABF86DQ28594188-F6295A31-9762-4BAA-A1A7-3D9307AA1E20Q28594574-62859875-5DD6-4782-AFFC-D980A5960718Q33403156-E6F16C36-7FD3-47A4-8831-083656B6A3CCQ34113413-F56528B1-97FC-4853-9470-597EEEC44925Q34596280-D512A743-9C94-4A0F-8660-CEFB89AE4A47Q41791610-68776D59-FC37-4F1D-89B2-CB8163E9F701
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Heat shock protein 5
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Heat shock protein 5
@en
type
label
Heat shock protein 5
@en
altLabel
78 kDa glucose-regulated protein
@en
BiP
@en
GRP-78
@en
HSP70 family protein 5
@en
Hspa5
@en
XAP-1 antigen
@en
binding-immunoglobulin protein
@en
endoplasmic reticulum chaperone BiP
@en
glucose regulated protein, 78 kDa
@en
heat shock 70 kDa protein 5
@en
prefLabel
Heat shock protein 5
@en
P361
P680
P681
P682
P705
P352
P31
P352
P361
P637
NP_001156906
P680
P681
P682
P702
P703
P705
ENSMUSP00000028222
ENSMUSP00000097747
ENSMUSP00000141966