Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells
about
Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4The final link: tapping the power of chemical genetics to connect the molecular and biologic functions of mitotic protein kinasesPolo-like kinase 1, on the rise from cell cycle regulation to prostate cancer developmentRho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseThe overlooked greatwall: a new perspective on mitotic controlCentralspindlin: at the heart of cytokinesisAugmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscissionAurora B kinase promotes cytokinesis by inducing centralspindlin oligomers that associate with the plasma membrane.The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic ComplementationAPC(CDH1) targets MgcRacGAP for destruction in the late M phaseOrbit/CLASP is required for myosin accumulation at the cleavage furrow in Drosophila male meiosisCdk1-dependent mitotic enrichment of cortical myosin II promotes cell rounding against confinementKinesins to the core: The role of microtubule-based motor proteins in building the mitotic spindle midzoneDynamic and multi-pharmacophore modeling for designing polo-box domain inhibitorsPlasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for CytokinesisDecoding Polo-like kinase 1 signaling along the kinetochore-centromere axisSelf-organization of intracellular gradients during mitosis.Plk4 is required for cytokinesis and maintenance of chromosomal stability.Polo kinase interacts with RacGAP50C and is required to localize the cytokinesis initiation complex.Self-organized partitioning of dynamically localized proteins in bacterial cell division.PRC1 controls spindle polarization and recruitment of cytokinetic factors during monopolar cytokinesis.The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration.RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4.High mitotic activity of Polo-like kinase 1 is required for chromosome segregation and genomic integrity in human epithelial cells.A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesisDiscovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP.Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stageCYK-4 regulates Rac, but not Rho, during cytokinesis.The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells.Polo-box domain: a versatile mediator of polo-like kinase function.Regulatory functional territory of PLK-1 and their substrates beyond mitosis.Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscissionRho GTPases as regulators of mitosis and cytokinesis in mammalian cells.What Drosophila spermatocytes tell us about the mechanisms underlying cytokinesisPolo-like kinase-activating kinases: Aurora A, Aurora B and what else?An anillin-Ect2 complex stabilizes central spindle microtubules at the cortex during cytokinesis.Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progressionThe Plk1-dependent phosphoproteome of the early mitotic spindleFeed-forward mechanism of converting biochemical cooperativity to mitotic processes at the kinetochore plateAnillin promotes astral microtubule-directed cortical myosin polarization.
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P2860
Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Plk1 self-organization and pri ...... set of division in human cells
@ast
Plk1 self-organization and pri ...... set of division in human cells
@en
Plk1 self-organization and pri ...... set of division in human cells
@en-gb
Plk1 self-organization and pri ...... set of division in human cells
@nl
type
label
Plk1 self-organization and pri ...... set of division in human cells
@ast
Plk1 self-organization and pri ...... set of division in human cells
@en
Plk1 self-organization and pri ...... set of division in human cells
@en-gb
Plk1 self-organization and pri ...... set of division in human cells
@nl
prefLabel
Plk1 self-organization and pri ...... set of division in human cells
@ast
Plk1 self-organization and pri ...... set of division in human cells
@en
Plk1 self-organization and pri ...... set of division in human cells
@en-gb
Plk1 self-organization and pri ...... set of division in human cells
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Plk1 self-organization and pri ...... set of division in human cells
@en
P2093
Chao Zhang
Drew M Lowery
Kevan M Shokat
Michael B Yaffe
Michael Repka
Prasad V Jallepalli
Steven A Carr
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1000111
P407
P577
2009-05-26T00:00:00Z