about
P688
Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responsesThioglycollate peritonitis in mice lacking C5, 5-lipoxygenase, or p47(phox): complement, leukotrienes, and reactive oxidants in acute inflammationStructural and functional criteria reveal a new nuclear import sequence on the 5-lipoxygenase proteinThe nuclear membrane organization of leukotriene synthesisIdentification of ALOX5 as a gene regulating adiposity and pancreatic function.Altered inflammatory responses in leukotriene-deficient mice5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ω-3 polyunsaturated fatty acids.5-Lipoxygenase plays a pivotal role in endothelial adhesion of monocytes via an increased expression of Mac-1.Arachidonate 5-lipoxygenase establishes adaptive humoral immunity by controlling primary B cells and their cognate T-cell help5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes.Critical role of 5-lipoxygenase and heme oxygenase-1 in wound healing.Conversion of pro-inflammatory murine Alox5 into an anti-inflammatory 15S-lipoxygenating enzyme by multiple mutations of sequence determinants.The inhibition of 5-lipoxygenase (5-LO) products leukotriene B4 (LTB4) and cysteinyl leukotrienes (cysLTs) modulates the inflammatory response and improves cutaneous wound healing.Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.Selective 5-lipoxygenase expression in Langerhans cells and impaired dendritic cell migration in 5-LO-deficient mice reveal leukotriene action in skinDeletion of Alox5 gene decreases osteogenic differentiation but increases adipogenic differentiation of mouse induced pluripotent stem cellsFunctional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme
P921
Q28505542-A442A112-9B14-4DCA-A8DD-34B3E22896A3Q28508084-EEFF214A-CE98-4BAC-921C-79094847838BQ28509450-A30A5D02-6B7C-4E57-A981-63804BA69A6FQ28513805-0EABD510-F62F-4490-A875-B48813EE367EQ33715656-F78B737F-BEE8-4590-BC56-FEAE2F41EE2EQ36008360-80BB553A-5B49-4396-9E79-61CD69D29456Q37011389-D2A0324A-E3FF-4F07-8495-16978F872427Q39145952-136A70A8-7A4A-4ADF-AF08-114CE3D8514CQ39609245-63613093-1587-431F-8024-CAF89BACDD96Q40974091-61252E1A-EF50-4CEC-9969-FCD02AD9199FQ43773669-5B113396-1604-4848-8E21-E53B7D8DF87DQ45903100-5A02695D-6B57-4280-B215-D734BD0F55F6Q48645152-9DF3A564-5502-481C-AE9C-94949E11F068Q52512619-6A22C0AA-93CA-4AD3-9469-F9883221E83AQ80058882-76E96015-A02B-497F-BC74-0D46E04C53CCQ88033644-6605D558-941D-4ECC-BF67-19C0A3457166Q90898325-91F1E2FB-71BC-4B5E-BC12-2245814D405E
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Arachidonate 5-lipoxygenase
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Arachidonate 5-lipoxygenase
@en
type
label
Arachidonate 5-lipoxygenase
@en
altLabel
5-lipoxygenase
@en
Alox5
@en
arachidonate 5-lipoxygenase
@en
prefLabel
Arachidonate 5-lipoxygenase
@en
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ENSMUSP00000026795
ENSMUSP00000130424
ENSMUSP00000130780
ENSMUSP00000145367