Overexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1
about
Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1A study of nuclear transcription factor-kappa B in childhood autismRapid activation of glutamate cysteine ligase following oxidative stress.Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway.Multi-faceted regulation of gamma-glutamylcysteine synthetase.Inhibiting NF-κB activation by small molecules as a therapeutic strategy.Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases.Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation.Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in miceDisruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell lineCaspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell DeathGallic acid induces the apoptosis of human osteosarcoma cells in vitro and in vivo via the regulation of mitogen-activated protein kinase pathways.Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cellsOverexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death.Immunology and oxidative stress in multiple sclerosis: clinical and basic approach.Cryptosporidium parvum at different developmental stages modulates host cell apoptosis in vitro.Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma.Mangifera indica (mango).Post-translational Activation of Glutamate Cysteine Ligase with Dimercaprol: A NOVEL MECHANISM OF INHIBITING NEUROINFLAMMATION IN VITRO.Increased cellular uptake of lauryl gallate loaded in superparamagnetic poly(methyl methacrylate) nanoparticles due to surface modification with folic acid.Anticancer activity of the phytomedicine DAS-77.TNF-α mediates mitochondrial uncoupling and enhances ROS-dependent cell migration via NF-κB activation in liver cells.The dual role of TLR3 in metastatic cell line.Inhibition of constitutive activity of nuclear transcription factor kappaB sensitizes doxorubicin-resistant cells to apoptosis.Oleandrin-mediated expression of Fas potentiates apoptosis in tumor cells.beta-D-Glucoside suppresses tumor necrosis factor-induced activation of nuclear transcription factor kappaB but potentiates apoptosis.Anethole blocks both early and late cellular responses transduced by tumor necrosis factor: effect on NF-kappaB, AP-1, JNK, MAPKK and apoptosis.Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling.The catalytic subunit of Drosophila glutamate-cysteine ligase is a nucleocytoplasmic shuttling protein.Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress.Anti-oxidant activity and attenuation of bladder hyperactivity by the flavonoid compound kaempferol.Oxygen radicals trigger activation of NF-kappaB and AP-1 and upregulation of ICAM-1 in reperfused canine heart.Hammerhead ribozyme against gamma-glutamylcysteine synthetase attenuates resistance to ionizing radiation and cisplatin in human T98G glioblastoma cells.The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain.Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase.Screening and identification of differentially expressed genes from chickens infected with Newcastle disease virus by suppression subtractive hybridization.Effects of Curcuminoids-Piperine Combination on Systemic Oxidative Stress, Clinical Symptoms and Quality of Life in Subjects with Chronic Pulmonary Complications Due to Sulfur Mustard: A Randomized Controlled Trial.The shoot-specific expression of gamma-glutamylcysteine synthetase directs the long-distance transport of thiol-peptides to roots conferring tolerance to mercury and arsenic.Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.Gallotannin regulates apoptosis and COX-2 expression via Akt and p38kinase pathway in human lung cancer cell line, A549
P2860
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P2860
Overexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Overexpression of gamma-glutam ...... appa B and activator protein-1
@ast
Overexpression of gamma-glutam ...... appa B and activator protein-1
@en
Overexpression of gamma-glutam ...... appa B and activator protein-1
@en-gb
Overexpression of gamma-glutam ...... appa B and activator protein-1
@nl
type
label
Overexpression of gamma-glutam ...... appa B and activator protein-1
@ast
Overexpression of gamma-glutam ...... appa B and activator protein-1
@en
Overexpression of gamma-glutam ...... appa B and activator protein-1
@en-gb
Overexpression of gamma-glutam ...... appa B and activator protein-1
@nl
prefLabel
Overexpression of gamma-glutam ...... appa B and activator protein-1
@ast
Overexpression of gamma-glutam ...... appa B and activator protein-1
@en
Overexpression of gamma-glutam ...... appa B and activator protein-1
@en-gb
Overexpression of gamma-glutam ...... appa B and activator protein-1
@nl
P2093
P2860
P921
P356
P1433
P1476
Overexpression of gamma-glutam ...... appa B and activator protein-1
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202811
P407
P577
1999-07-29T00:00:00Z
P5875
P6179
1037539129