The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
about
Epstein-Barr virus-negative boys with non-Hodgkin lymphoma are mutated in the SH2D1A gene, as are patients with X-linked lymphoproliferative disease (XLP)Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patientsA novel immunoglobulin superfamily receptor (19A) related to CD2 is expressed on activated lymphocytes and promotes homotypic B-cell adhesionA "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndromeSLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cellsIncreased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiationThe X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activationThe phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cellsSelective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative diseaseMeasles virus infects and suppresses proliferation of T lymphocytes from transgenic mice bearing human signaling lymphocytic activation moleculeProgress and problems in understanding and managing primary Epstein-Barr virus infectionsXIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative diseaseDual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and toleranceNTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative diseaseX-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cellsA novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinaseThe X-linked lymphoproliferative syndrome gene product SH2D1A associates with p62dok (Dok1) and activates NF-kappa BSiglecs in the immune systemThe molecular pathology of primary immunodeficienciesThe Role of Gammaherpesviruses in Cancer PathogenesisResponses to Microbial Challenges by SLAMF ReceptorsSevere infectious diseases of childhood as monogenic inborn errors of immunityCytotoxic granule secretion by lymphocytes and its link to immune homeostasisHemophagocytic lymphohistiocytosis: an update on diagnosis and pathogenesisSolution structure of tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1X-linked lymphoproliferative syndromes: brothers or distant cousins?NK Cell Influence on the Outcome of Primary Epstein-Barr Virus InfectionThe Host Cell Receptors for Measles Virus and Their Interaction with the Viral Hemagglutinin (H) ProteinInfluence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell functionCD84 negatively regulates IgE high-affinity receptor signaling in human mast cellsFine specificity and molecular competition in SLAM family receptor signallingCIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2)Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene productInteraction domains: from simple binding events to complex cellular behaviorDual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptorsA spectrum of mutations in SH2D1A that causes X-linked lymphoproliferative disease and other Epstein-Barr virus-associated illnessesAssociation of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent on phosphoinositide 3-kinase
P2860
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P2860
The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@ast
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@en
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@en-gb
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@nl
type
label
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@ast
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@en
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@en-gb
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@nl
prefLabel
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@ast
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@en
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@en-gb
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@nl
P2093
P3181
P356
P1433
P1476
The X-linked lymphoproliferati ...... d through the co-receptor SLAM
@en
P2093
C Terhorst
J E De Vries
L Notarangelo
P2888
P304
P3181
P356
10.1038/26683
P407
P577
1998-10-01T00:00:00Z
P5875
P6179
1018885402