Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
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Angiopoietin-1 is an apoptosis survival factor for endothelial cellsRegulation of endothelium-derived nitric oxide production by the protein kinase AktA phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cellsHomeostatic modulation of cell surface KDR and Flt1 expression and expression of the vascular endothelial cell growth factor (VEGF) receptor mRNAs by VEGFDirect identification of a major autophosphorylation site on vascular endothelial growth factor receptor Flt-1 that mediates phosphatidylinositol 3'-kinase bindingIsolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathwayVascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cellsTIMAP promotes angiogenesis by suppressing PTEN-mediated Akt inhibition in human glomerular endothelial cellsThe zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesisContact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survivalThrombospondin 2 inhibits microvascular endothelial cell proliferation by a caspase-independent mechanism.The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesisThe Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cellsRapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cellsContinuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicityAssociation between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicityAkt1 in endothelial cell and angiogenesisSolenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesisNovel hepatocyte growth factor (HGF) binding domains on fibronectin and vitronectin coordinate a distinct and amplified Met-integrin induced signalling pathway in endothelial cellsAnti-inflammatory, antiapoptotic, and antioxidant activity of fluoxetineThe Potential Role of Kallistatin in the Development of Abdominal Aortic AneurysmProfile of bevacizumab in the treatment of platinum-resistant ovarian cancer: current perspectivesPlacental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentFucoidan as a Potential Therapeutic for Major Blinding Diseases--A HypothesisProstate cancer metastasis: roles of recruitment and reprogramming, cell signal network and three-dimensional growth characteristicsBiomarkers in triple negative breast cancer: A reviewTumour Angiogenesis and Angiogenic Inhibitors: A ReviewNetrin-1 as a novel therapeutic target in cardiovascular disease: to activate or inhibit?Single Nucleotide Polymorphism in Patients with Moyamoya DiseasemiRNAs in breast cancer tumorigenesis (Review)The role of vascular endothelial growth factor a polymorphisms in breast cancerSignaling pathways in the development of infantile hemangiomaVascular endothelial growth factor-B in physiology and diseaseVascular Endothelial Growth Factor and Angiogenesis in the Regulation of Cutaneous Wound RepairGastric Cancer: New Drugs - New StrategiesAAV2 delivery of Flt23k intraceptors inhibits murine choroidal neovascularizationRedox modification of proteins as essential mediators of CNS autophagy and mitophagy.The critical role of Akt in cardiovascular function
P2860
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P2860
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@ast
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@en
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@en-gb
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@nl
type
label
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@ast
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@en
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@en-gb
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@nl
prefLabel
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@ast
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@en
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@en-gb
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@nl
P2093
P921
P3181
P356
P1476
Vascular endothelial growth fa ...... ement for Flk-1/KDR activation
@en
P2093
A McMurtrey
H P Gerber
J Kowalski
P304
P3181
P356
10.1074/JBC.273.46.30336
P407
P577
1998-11-13T00:00:00Z