A C-terminal di-leucine is required for localization of the Menkes protein in the trans-Golgi network
about
Signals regulating trafficking of Menkes (MNK; ATP7A) copper-translocating P-type ATPase in polarized MDCK cellsBinding of copper(I) by the Wilson disease protein and its copper chaperoneA single PDZ domain protein interacts with the Menkes copper ATPase, ATP7A. A new protein implicated in copper homeostasisBiochemical basis of regulation of human copper-transporting ATPasesMolecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypesMolecular mechanism of copper transport in Wilson disease.Forty Years of Clathrin-coated VesiclesCellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disordersThe copper toxicosis gene product Murr1 directly interacts with the Wilson disease proteinStructure, function, and regulation of a subfamily of mouse zinc transporter genesATP7A-related copper transport diseases-emerging concepts and future trendsA novel frameshift mutation in exon 23 of ATP7A (MNK) results in occipital horn syndrome and not in Menkes diseaseMammary gland copper transport is stimulated by prolactin through alterations in Ctr1 and Atp7A localizationDefective copper-induced trafficking and localization of the Menkes protein in patients with mild and copper-treated classical Menkes diseasePolarized sorting of the copper transporter ATP7B in neurons mediated by recognition of a dileucine signal by AP-1.Kinky hair, kinky vessels, and bladder diverticula in Menkes disease.Metal ion transporters in mammals: structure, function and pathological implications.ATP7A trafficking and mechanisms underlying the distal motor neuropathy induced by mutations in ATP7A.A conditional mutation affecting localization of the Menkes disease copper ATPase. Suppression by copper supplementation.Drug targets in Menkes disease - prospective developments.Direct interactions of adaptor protein complexes 1 and 2 with the copper transporter ATP7A mediate its anterograde and retrograde traffickingAltered intracellular localization and valosin-containing protein (p97 VCP) interaction underlie ATP7A-related distal motor neuropathyTrafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2-, AP-1-, and Rab22-dependent stepsMetal ions in macrophage antimicrobial pathways: emerging roles for zinc and copperApical targeting and Golgi retention signals reside within a 9-amino acid sequence in the copper-ATPase, ATP7B.Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis.Advances in the understanding of mammalian copper transporters.An overview and update of ATP7A mutations leading to Menkes disease and occipital horn syndrome.Golgi in copper homeostasis: a view from the membrane trafficking field.The role of GMXCXXC metal binding sites in the copper-induced redistribution of the Menkes protein.Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters.Effects of copper on CHO cells: cellular requirements and product quality considerations.Trafficking of a secretory granule membrane protein is sensitive to copper.Copper homoeostasis in Drosophila melanogaster S2 cells.Characterization of the Menkes protein copper-binding domains and their role in copper-induced protein relocalization.Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network.Distinct reading of different structural determinants modulates the dileucine-mediated transport steps of the lysosomal membrane protein LIMPII and the insulin-sensitive glucose transporter GLUT4.Copper stimulates trafficking of a distinct pool of the Menkes copper ATPase (ATP7A) to the plasma membrane and diverts it into a rapid recycling pool.Metallo-pathways to Alzheimer's disease: lessons from genetic disorders of copper trafficking.13 novel putative mutations in ATP7A found in a cohort of 25 Italian families.
P2860
Q24299890-D43E6965-CEAF-4865-9C61-C944096927E4Q24304146-20A7F072-5719-4FC2-9925-2EEE8941E866Q24310759-DD0E66EC-D920-4BB6-8023-0CC07B73089FQ24569563-373CAFBC-733E-4CFE-865F-EA2757497B76Q24647056-62F66499-4B37-416D-9CD8-E021B3BE8D05Q24812338-A71320B4-3D1A-4A23-A782-CAFBA56CFF07Q26781439-109D0C03-4204-4EC5-9A7A-51C1A0C37C4DQ27003886-0E54737A-FF01-403E-A1F8-A4532347D02FQ28206233-20526F8D-D63D-4CF7-ADF3-4E46FC35D635Q28207124-C15B5E18-73ED-4A2E-8F6D-5CEC7F219F1BQ28302938-2886658F-FA81-418A-B168-78DF8EED88C8Q28367963-8E93A1FF-74FB-4509-9D48-1A04CA9B6923Q28567719-D956B40E-A237-471E-93C6-6B876C49A2D3Q28609317-82F8F6FC-7878-4A58-9278-41FDE3167A3BQ30615545-81952813-2588-4B1C-98FE-6144533279C9Q33562182-9639CB77-C055-470B-9F70-2382E99E4E38Q33663264-B422CE4C-6F28-48F3-9080-97D65006BF08Q33696716-4674D686-AF4A-4C5C-8F62-6AD24C77405FQ34148762-ED5420EE-004C-480F-BAD8-381FACCB0EB7Q35050435-A00BD9BA-CDFD-4F10-8547-E9F895BEF77EQ35253046-8252711A-F77C-4BB7-A415-AEC7F1BE982AQ35856248-681DAFDA-818E-4EFC-8E3D-E77170F0A44BQ36887422-75CCA08A-8CB9-446A-835C-8557D1133BE7Q37016266-CEB465DC-6230-4E9E-AE1D-0E56FF4EE9A8Q37100260-1082B0E4-01E4-4F44-8E11-DCC84EE520CDQ37112824-02BBF638-E31F-4076-B48D-EBD0B3AF51BBQ37983830-51059F6A-00DC-458E-BD2B-F07137C58959Q38071046-8A51E50A-D1F4-45D8-846A-F014BB0F3710Q38121020-FFDE83E6-26E1-4000-B6B5-9C09D4447E88Q38326201-87EDF8E9-2DAB-4979-8834-22AD831F938BQ38543983-DB0351EB-227F-46B5-A0B3-E6E236B2E016Q38948246-7B39B94F-2FC4-4D96-AA99-9FA14752E9D7Q40121002-FEA55021-EA8D-4297-9FAF-DF78B0F01260Q40538435-5E5BF5AD-6083-44D6-B8B6-44F93A178949Q40942795-6930431A-0599-4113-BDF5-C3E9AAFCD0B2Q41105245-2C45D708-DCF7-40A9-B2F4-B75AB6486182Q42797706-6009E415-543E-46AB-A0B7-5D0636BB08FDQ43003580-F7EB27B1-4339-43D0-9DC3-969DCC493BC4Q47985612-4BFD40ED-0C92-4253-AEEC-C46BDA4BD95CQ48221091-94E8B2CE-2398-4006-A9B8-29E12A28A740
P2860
A C-terminal di-leucine is required for localization of the Menkes protein in the trans-Golgi network
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@ast
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@en
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@en-gb
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@nl
type
label
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@ast
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@en
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@en-gb
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@nl
prefLabel
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@ast
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@en
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@en-gb
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@nl
P2093
P356
P1476
A C-terminal di-leucine is req ...... ein in the trans-Golgi network
@en
P2093
J Camakaris
J F Mercer
M Greenough
M J Petris
S LaFontaine
P304
P356
10.1093/HMG/7.13.2063
P407
P577
1998-12-01T00:00:00Z