SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents
about
Ribosomal protein S27L is a direct p53 target that regulates apoptosisBTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligaseThe role of cullin 5-containing ubiquitin ligasesGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesYeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulationThe conserved RING-H2 finger of ROC1 is required for ubiquitin ligationPhosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1Promotion of S-phase entry and cell growth under serum starvation by SAG/ROC2/Rbx2/Hrt2, an E3 ubiquitin ligase component: association with inhibition of p27 accumulationAcid sphingomyelinase as target of Lycium Chinense: promising new action for cell healthGenome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection.Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesisMolecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p.Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis.p53CP is p51/p63, the third member of the p53 gene family: partial purification and characterization.The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligationUbiquitination by SAG regulates macrophage survival/death and immune response during infection.Inactivation of SAG E3 ubiquitin ligase blocks embryonic stem cell differentiation and sensitizes leukemia cells to retinoid acid.RING finger Z protein of lymphocytic choriomeningitis virus (LCMV) inhibits transcription and RNA replication of an LCMV S-segment minigenome.Small RING Finger Proteins RBX1 and RBX2 of SCF E3 Ubiquitin Ligases: The Role in Cancer and as Cancer TargetsTargeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapyInactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalizationE3 ubiquitin ligases as cancer targets and biomarkers.SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protectionSAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradationA fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cellsErbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesisSCF E3 ubiquitin ligases as anticancer targets.SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB.PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway.RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27Role of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases in skin cancer.Genetic architecture of human fibrotic diseases: disease risk and disease progression.Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis.Targeted disruption of Drosophila Roc1b reveals functional differences in the Roc subunit of Cullin-dependent E3 ubiquitin ligases.Tat-fused recombinant human SAG prevents dopaminergic neurodegeneration in a MPTP-induced Parkinson's disease model.RNF7 knockdown inhibits prostate cancer tumorigenesis by inactivation of ERK1/2 pathway.Radiosensitization of Cancer Cells by Inactivation of Cullin-RING E3 Ubiquitin Ligases.Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase.Role of E3 ubiquitin ligases in lung cancer.Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis.
P2860
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P2860
SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@ast
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@en
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@en-gb
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@nl
type
label
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@ast
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@en
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@en-gb
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@nl
prefLabel
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@ast
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@en
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@en-gb
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@nl
P2093
P2860
P921
P3181
P356
P1476
SAG, a novel zinc RING finger ...... ptosis induced by redox agents
@en
P2093
C L Bisgaier
P2860
P304
P3181
P356
10.1128/MCB.19.4.3145
P407
P577
1999-04-01T00:00:00Z